Palladium(0)-catalyzed benzylation of H-phosphonate diesters: An efficient entry to benzylphosphonates

• A new, efficient method for the synthesis of benzylphosphonate diesters via a palladium(0)-catalyzed cross-coupling reaction between benzyl halides and H-phosphonate diesters, using Pd(OAc)2 as a palladium source and Xantphos as a supporting ligand, has been developed.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Andra medicinska och farmaceutiska grundvetenskaper (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Other Basic Medicine (hsv//eng)

Nyckelord

benzylphosphonates

palladium cross-coupling

H-phos­phonates

C-phosphonates

Chemistry

Kemi

organisk kemi

Organic Chemistry

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)