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Determination of pe...
Determination of perfluoroalkyl carboxylic, sulfonic, and phosphonic acids in food
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- Ullah, Shahid, 1977- (författare)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
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- Alsberg, Tomas (författare)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
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- Vestergren, Robin (författare)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
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- Berger, Urs (författare)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
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(creator_code:org_t)
- 2012-09-06
- 2012
- Engelska.
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Ingår i: Analytical and Bioanalytical Chemistry. - : Springer Science and Business Media LLC. - 1618-2642 .- 1618-2650. ; 404:8, s. 2193-2201
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- A sensitive and accurate method was developed and validated for simultaneous analysis of perfluoroalkyl carboxylic acids, sulfonic acids, and phosphonic acids (PFPAs) at low picograms per gram concentrations in a variety of food matrices. The method employed extraction with acetonitrile/water and cleanup on a mixed-mode co-polymeric sorbent (C8 + quaternary amine) using solid-phase extraction. High-performance liquid chromatographic separation was achieved on a C18 column using a mobile phase gradient containing 5 mM 1-methyl piperidine for optimal chromatographic resolution of PFPAs. A quadrupole time-of-flight high-resolution mass spectrometer operating in negative ion mode was used as detector. Method detection limits were in the range of 0.002 to 0.02 ng g(-1) for all analytes. Sample preparation (extraction and cleanup) recoveries at a spiking level of 0.1 ng g(-1) to a baby food composite were in the range of 59 to 98 %. A strong matrix effect was observed in the analysis of PFPAs in food extracts, which was tentatively assigned to sorption of PFPAs to the injection vial in the solvent-based calibration standard. The method was successfully applied to a range of different food matrices including duplicate diet samples, vegetables, meat, and fish samples.
Ämnesord
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Nyckelord
- PFCAs
- PFSAs
- PFPAs
- Food samples
- HPLC
- HRMS
- Applied Environmental Science
- tillämpad miljövetenskap
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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