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Gestational age-rel...
Gestational age-related changes in the peripheral blood cell composition of sub-Saharan African women
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Ibitokou, Samad (författare)
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Brutus, Laurent (författare)
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Vianou, Bertin (författare)
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Oesterholt, Mayke (författare)
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Massougbodji, Achille (författare)
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Deloron, Philippe (författare)
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- Troye-Blomberg, Marita (författare)
- Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut
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Fievet, Nadine (författare)
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Luty, Adrian J. F. (författare)
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(creator_code:org_t)
- Elsevier BV, 2013
- 2013
- Engelska.
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Ingår i: Journal of Reproductive Immunology. - : Elsevier BV. - 0165-0378 .- 1872-7603. ; 98:1-2, s. 21-28
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Gestational age-related changes in the cellular composition of peripheral blood have not been described in sub-Saharan African settings. We conducted longitudinal cohort studies in Beninese and Tanzanian mothers with quantification of peripheral blood mononuclear cell-types ex vivo using flow cytometry. Between the second trimester and delivery the frequency of CD4(+) T cells declined significantly, contrasting with a non-significant increase in CD8(+) T cells, but no changes in T-regulatory, NK or NKT cell frequencies. Antigen-presenting cell profiles were also unaltered, although non-significant trends were evident. These changes resemble in some respects those reported during pregnancies in developed countries, but differ in others.
Ämnesord
- NATURVETENSKAP -- Biologi -- Immunologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Immunology (hsv//eng)
Nyckelord
- Pregnancy
- Peripheral blood mononuclear cells
- African women
- Longitudinal cohort study
- Lymphocytes
- Antigen-presenting cells
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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