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Localization of typ...
Localization of type X collagen in the intervertebral disc of mature beagle dogs.
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- Lammi, Pirkko (författare)
- Department of Clinical Chemistry, Kuopio University Hospital, Kuopio, Finland
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- Inkinen, Ritva (författare)
- Department of Anatomy, University of Kuopio, Kuopio, Finland
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- von der Mark, Klaus (författare)
- Institute for Experimental Medicine, University of Erlangen-Nurenberg, Erlangen, Germany
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- Puustjärvi, K (författare)
- Department of Physical Medicine and Rehabilitation, Kuopio University Hospital, Kuopio, Finland
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- Arokoski, Jari (författare)
- Department of Physical Medicine and Rehabilitation, Kuopio University Hospital, Kuopio, Finland
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- Hyttinen, Mika (författare)
- Department of Anatomy, University of Kuopio, Kuopio, Finland
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- Lammi, Mikko, 1961- (författare)
- Department of Anatomy, University of Kuopio, Kuopio, Finland,Chondrogenic and Osteogenic Differentiation Group
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(creator_code:org_t)
- Elsevier, 1998
- 1998
- Engelska.
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Ingår i: Matrix Biology. - : Elsevier. - 0945-053X .- 1569-1802. ; 17:6, s. 449-453
- Relaterad länk:
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http://www.sciencedi...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Type X collagen expression in intervertebral disc of young adult beagle dogs (n = 10) was studied. Type X collagen was immunostained mainly pericellularly in the central area of the vertebral endplate, but interterritorial staining there was also present. Annulus fibrosus and nucleus pulposus did not usually stain for type X collagen. However, immunostaining of nucleus pulposus for type X collagen with a simultaneous expression of collagen alpha1(X) mRNA was observed in one dog. A weak staining was observed in two other animals with a weak collagen alpha1(X) mRNA signal. In annulus fibrosus, lamellar staining was observed in two dogs. In three animals, type X collagen mRNAs were observed in the outer edge of the annulus fibrosus, but immunohistochemical staining did not always correlate with in situ hybridization signals. In conclusion, intervertebral disc type X collagen was mainly expressed in the cartilaginous endplate. In some apparently healthy animals there was type X collagen expression in the nucleus pulposus and also in the annulus fibrosus.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Cellbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Cell Biology (hsv//eng)
Nyckelord
- Dog
- intervertebral disc
- type X collagen
- cell research
- cellforskning
- ortopedi
- Orthopaedics
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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