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Increase of decorin...
Increase of decorin content in articular cartilage following running.
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- Visser, Nanette (författare)
- Jan van Breemen Institute , Amsterdam, The Netherlands;
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- de Koning, Margret (författare)
- Jan van Breemen Institute , Amsterdam, The Netherlands
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- Lammi, Mikko, 1961- (författare)
- Department of Anatomy, University of Kuopio, Kuopio, Finland,Chondrogenic and Osteogenic Differentiation Group
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- Häkkinen, Tomi (författare)
- Department of Anatomy, University of Kuopio, Kuopio, Finland
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- Tammi, Markku (författare)
- Department of Anatomy, University of Kuopio, Kuopio, Finland
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- van Kampen, G. P. Jos (författare)
- Jan van Breemen Institute , Amsterdam, The Netherlands
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(creator_code:org_t)
- Informa Healthcare, 1998
- 1998
- Engelska.
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Ingår i: Connective Tissue Research. - : Informa Healthcare. - 0300-8207 .- 1607-8438. ; 37:3-4, s. 295-302
- Relaterad länk:
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http://informahealth...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- The effect of long distance running exercise (40 km/day for 15 weeks, five days a week) on the decorin content of articular cartilage from the knee joint was studied in female beagle dogs. Samples from load bearing sites on the lateral plateau of the tibia (TL), and pooled material from two minimum load bearing sites on the posterior section of lateral (FLP) and medial (FMP) femoral condyles were analyzed. The running exercise protocol did not lead to significant changes in the overall glycosaminoglycan content of the cartilage. However, the amount of decorin significantly increased in the TL samples, and also in the FMP pool. These results support earlier in vitro observations that decorin synthesis is stimulated by loading, independent of the synthesis of aggrecan.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Nyckelord
- Articualr cartilage
- dog
- proteogylcans
- decorin
- exercise
- biokemi
- Biochemistry
- cell research
- cellforskning
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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