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Prescribed psychiat...
Prescribed psychiatric medication among multiple sclerosis patients before and after disability pension : a register study with matched controls
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- Brenner, Philip (författare)
- Karolinska Institutet
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- Mittendorfer-Rutz, Ellenor (författare)
- Karolinska Institutet
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- Jokinen, Jussi (författare)
- Karolinska Institutet,Umeå universitet,Psykiatri,Department of Clinical Neuroscience, Karolinska Institutet, Center for Psychiatry Research, Karolinska Universitetssjukhuset R5:00, 171 77 Stockholm, Sweden,Department of Clinical Neuroscience, Karolinska Institutet; Center for Psychiatry Research, Karolinska Universitetssjukhuset; Department of Clinical Sciences, Umeå University
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- Alexanderson, Kristina (författare)
- Karolinska Institutet
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- Hillert, Jan (författare)
- Division of Neurology, Department of Clinical Neuroscience, Karolinska Institutet
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- Tinghög, Petter (författare)
- Karolinska Institutet,Röda Korsets Högskola,Avdelningen Medicin och Folkhälsa
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(creator_code:org_t)
- 2016-05-11
- 2016
- Engelska.
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Ingår i: Social Psychiatry and Psychiatric Epidemiology. - : Springer Nature. - 0933-7954 .- 1433-9285. ; 51:7, s. 1047-1054
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Many multiple sclerosis (MS) patients of working ages have psychiatric comorbidity, and 60 % are on disability pension (DP). It is unknown how DP is associated with MS patients' mental health. The objective of this study was to investigate the association between prescriptions of psychiatric medication and time before and after receiving full-time DP in MS patients compared with matched controls. Nationwide Swedish registers were used to identify 3836 MS patients who were granted DP in 2000-2012 and 19,180 DP controls matched on socio-demographic variables by propensity scores. Patients and controls were organized in groups by year granted DP. Adjusted odds ratios (ORs) with 95 % confidence intervals (CIs) were calculated for being prescribed selective serotonin reuptake inhibitors (SSRIs), benzodiazepines, or sleeping agents in 2006. Both patients and controls, who were not yet on DP in the study year of 2006, had lower OR compared with those who were granted DP in the same year. The OR increased when being closer to DP. MS patients, who had been granted DP 5-6 years earlier, had a higher risk for prescription of benzodiazepines (OR 1.72; 95 % CI 1.16-2.57) than controls (OR 1.14; 95 % CI 1.14-1.18). These patients also had a higher risk for SSRI prescription when compared directly with controls (OR 1.76; 95 % CI 1.44-2.15). MS patients have substantially higher odds ratios for being prescribed psychiatric drugs after DP than other disability pensioners. Further research on the association of DP with the mental health of MS patients is warranted.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Multiple sclerosis
- Disability pension
- Sick leave
- Epidemiology
- Depression
- Serotonin uptake hibitors
- Benzodiazepines
- Hypnotics and sedatives
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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