Sökning: id:"swepub:oai:DiVA.org:umu-137796" >
Diabetes and male s...
Diabetes and male sex are key risk factor correlates of the extent of coronary artery calcification : a Euro-CCAD study
-
- Nicoll, Rachel (författare)
- Umeå universitet,Medicin,Heart Centre
-
Zhao, Ying (författare)
-
- Wiklund, Urban (författare)
- Umeå universitet,Institutionen för strålningsvetenskaper
-
visa fler...
-
Diederichsen, Axel (författare)
-
Mickley, Hans (författare)
-
Ovrehus, Kristian (författare)
-
Zamorano, Jose (författare)
-
Gueret, Pascal (författare)
-
Schmermund, Axel (författare)
-
Maffei, Erica (författare)
-
Cademartiri, Filippo (författare)
-
Budoff, Matt (författare)
-
- Henein, Michael (författare)
- Umeå universitet,Medicin,Heart Centre
-
visa färre...
-
(creator_code:org_t)
- Elsevier, 2017
- 2017
- Engelska.
-
Ingår i: Journal of diabetes and its complications. - : Elsevier. - 1056-8727 .- 1873-460X. ; 31:7, s. 1096-1102
- Relaterad länk:
-
https://escholarship...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Background and Aims: Although much has been written about the conventional cardiovascular risk factor correlates of the extent of coronary artery calcification (CAC), few studies have been carried out on symptomatic patients. This paper assesses the potential ability of risk factors to associate with an increasing CAC score. Methods: From the European Calcific Coronary Artery Disease (Euro-CCAD) cohort, we retrospectively investigated 6309 symptomatic patients, 62% male, from Denmark, France, Germany, Italy, Spain and the USA. All had conventional cardiovascular risk factor assessment and CI scanning for CAC scoring. Results: Among all patients, male sex (OR = 4.85, p < 0.001) and diabetes (OR = 236, p < 0.001) were the most important risk factors of CAC extent, with age, hypertension, dyslipidemia and smoking also showing a relationship. Among patients with CAC, age, diabetes, hypertension and dyslipidemia were associated with an increasing CAC score in males and females, with diabetes being the strongest dichotomous risk factor (p < 0.001 for both). These results were echoed in quantile regression, where diabetes was consistently the most important correlate with CAC extent in every quantile in both males and females. To a lesser extent, hypertension and dyslipidemia were also associated in the high CAC quantiles and the low CAC quantiles respectively. Conclusion: In addition to age and male sex in the total population, diabetes is the most important correlate of CAC extent in both sexes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Nyckelord
- Coronary calcification extent
- Risk factors
- Diabetes
- Gender
- Hypertension
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Nicoll, Rachel
-
Zhao, Ying
-
Wiklund, Urban
-
Diederichsen, Ax ...
-
Mickley, Hans
-
Ovrehus, Kristia ...
-
visa fler...
-
Zamorano, Jose
-
Gueret, Pascal
-
Schmermund, Axel
-
Maffei, Erica
-
Cademartiri, Fil ...
-
Budoff, Matt
-
Henein, Michael
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Endokrinologi oc ...
- Artiklar i publikationen
-
Journal of diabe ...
- Av lärosätet
-
Umeå universitet