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The skin microbiome :
The skin microbiome : impact of modern environments on skin ecology, barrier integrity, and systemic immune programming
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Prescott, Susan L. (författare)
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Larcombe, Danica-Lea (författare)
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Logan, Alan C. (författare)
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- West, Christina (författare)
- Umeå universitet,Pediatrik,World Univ Network, In FLAME Global Network, West New York, NJ USA
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Burks, Wesley (författare)
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Caraballo, Luis (författare)
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Levin, Michael (författare)
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Van Etten, Eddie (författare)
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Horwitz, Pierre (författare)
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Kozyrskyj, Anita (författare)
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Campbell, Dianne E. (författare)
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(creator_code:org_t)
- BIOMED CENTRAL LTD, 2017
- 2017
- Engelska.
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Ingår i: World Allergy Organization Journal. - : BIOMED CENTRAL LTD. - 1939-4551. ; 10
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Skin barrier structure and function is essential to human health. Hitherto unrecognized functions of epidermal keratinocytes show that the skin plays an important role in adapting whole-body physiology to changing environments, including the capacity to produce a wide variety of hormones, neurotransmitters and cytokine that can potentially influence whole-body states, and quite possibly, even emotions. Skin microbiota play an integral role in the maturation and homeostatic regulation of keratinocytes and host immune networks with systemic implications. As our primary interface with the external environment, the biodiversity of skin habitats is heavily influenced by the biodiversity of the ecosystems in which we reside. Thus, factors which alter the establishment and health of the skin microbiome have the potential to predispose to not only cutaneous disease, but also other inflammatory non-communicable diseases (NCDs). Indeed, disturbances of the stratum corneum have been noted in allergic diseases (eczema and food allergy), psoriasis, rosacea, acne vulgaris and with the skin aging process. The built environment, global biodiversity losses and declining nature relatedness are contributing to erosion of diversity at a micro-ecological level, including our own microbial habitats. This emphasises the importance of ecological perspectives in overcoming the factors that drive dysbiosis and the risk of inflammatory diseases across the life course.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Nyckelord
- Skin
- Microbiome
- Microbiota
- Inflammation
- Allergy
- Cytokines
- Biodiversity
- Colonisation
- Antibiotics
- DOHaD
- Ecosystems
- Prevention
- NCDs
- Caesarean section
- Pregnancy
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Prescott, Susan ...
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Larcombe, Danica ...
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Logan, Alan C.
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West, Christina
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Burks, Wesley
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Caraballo, Luis
-
visa fler...
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Levin, Michael
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Van Etten, Eddie
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Horwitz, Pierre
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Kozyrskyj, Anita
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Campbell, Dianne ...
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Dermatologi och ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Lungmedicin och ...
- Artiklar i publikationen
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World Allergy Or ...
- Av lärosätet
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Umeå universitet