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A Global Overview o...
A Global Overview of Precision Medicine in Type 2 Diabetes
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- Fitipaldi, Hugo (författare)
- Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups
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- McCarthy, Mark I. (författare)
- University of Oxford,Wellcome Trust Centre for Human Genetics
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- Florez, Jose C. (författare)
- Broad Institute,Massachusetts General Hospital,Harvard University
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- Franks, Paul W. (författare)
- Umeå University,Lund University,Lunds universitet,Umeå universitet,Medicin,Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Skåne University Hospital, Malmö, Sweden; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U.K; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups
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(creator_code:org_t)
- 2018-09-12
- 2018
- Engelska.
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Ingår i: Diabetes. - : American Diabetes Association. - 0012-1797 .- 1939-327X. ; 67:10, s. 1911-1922
- Relaterad länk:
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https://doi.org/10.2...
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https://diabetes.dia...
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.2...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- The detailed characterization of human biology and behaviors is now possible at scale owing to innovations in biomarkers, bioimaging, and wearable technologies; "big data" from electronic medical records, health insurance databases, and other platforms becoming increasingly accessible; and rapidly evolving computational power and bioinformatics methods. Collectively, these advances are creating unprecedented opportunities to better understand diabetes and many other complex traits. Identifying hidden structures within these complex data sets and linking these structures to outcome data may yield unique insights into the risk factors and natural history of diabetes, which in turn may help optimize the prevention and management of the disease. This emerging area is broadly termed "precision medicine." In this Perspective, we give an overview of the evidence and barriers to the development and implementation of precision medicine in type 2 diabetes. We also discuss recently presented paradigms through which complex data might enhance our understanding of diabetes and ultimately our ability to tackle the disease more effectively than ever before.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Diabetes
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