Sökning: id:"swepub:oai:DiVA.org:umu-158841" >
Passive leg-lifting...
Passive leg-lifting in heart failure patients predicts exercise-induced rise in left ventricular filling pressures
-
- Tossavainen, Erik, 1977- (författare)
- Umeå universitet,Kardiologi,Umea Univ, Dept Publ Hlth & Clin Med, Cardiol, S-90185 Umea, Sweden
-
- Wikström, Gerhard (författare)
- Uppsala universitet,Kardiologi
-
- Henein, Michael Y. (författare)
- Umeå universitet,Kardiologi,Umea Univ, Dept Publ Hlth & Clin Med, Cardiol, S-90185 Umea, Sweden
-
visa fler...
-
- Lundqvist, M. (författare)
- Uppsala universitet,Kardiologi
-
- Wiklund, Urban (författare)
- Umeå universitet,Radiofysik,Umea Univ, Dept Radiat Sci, Biomed Engn, Umea, Sweden
-
- Lindqvist, Per (författare)
- Umeå universitet,Klinisk fysiologi,Umea Univ, Dept Surg & Perioperat Sci, Clin Physiol, Umea, Sweden
-
visa färre...
-
(creator_code:org_t)
- 2019-07-31
- 2020
- Engelska.
-
Ingår i: Clinical Research in Cardiology. - : Springer. - 1861-0684 .- 1861-0692. ; 109:4, s. 498-507
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://umu.diva-por... (primary) (Raw object)
-
https://link.springe...
-
https://uu.diva-port... (primary) (Raw object)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
visa färre...
Abstract
Ämnesord
Stäng
- Aim: The aim of this study was to assess PCWP with passive leg-lifting (PLL) and exercise, in two groups of patients presenting with normal left ventricular ejection fraction (LVEF); one group with elevated NT-proBNP (eBNP), and one with normal NT-proBNP (nBNP) plasma concentration.Methods and results: Fifty-one patients with eBNP (NT-proBNP ≥ 125 ng/l) and LVEF > 50%, were investigated and compared with 34 patients with nBNP (NT-proBNP < 125 ng/l) and LVEF > 50%. Both groups underwent right heart catheterization (RHC) at rest, PLL and exercise. From RHC, mean pulmonary arterial pressure (mPAP), cardiac output (CO), and PCWP were measured. All nBNP patients had PCWP < 15 mmHg at rest, and a PCWP of < 25 mmHg with PLL and during exercise. Patients with eBNP had higher (p < 0.01) resting mPAP, PCWP, and mPAP/CO. These values increased with exercise; however, CO increased less in comparison with nBNP patients (p = 0.001). 20% of patients with eBNP had a PCWP > 15 mmHg at rest, this percentage increased to 47% with PLL and 41% had a PCWP > 25 mmHg during exercise. Of those with PCWP > 25 mmHg during exercise, 91% had a PCWP > 15 mmHg with PLL. A PCWP > 15 mmHg on PLL had a 91% sensitivity and 92% specificity in predicting exercise-induced PCWP of > 25 mmHg.Conclusion: In patients presenting with eBNP, PLL can predict which patients will develop elevated PCWP with exercise. These findings highlight the role of stress assessment.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Passive leg-lifting
- Exercise
- Elevated filling pressures
- Pulmonary hypertension
- Heart failure
- Cardiology
- kardiologi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas