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Virulence and Patho...
Virulence and Pathogenicity Properties of Aggregatibacter actinomycetemcomitans
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- Belibasakis, Georgios N (författare)
- Karolinska Institutet
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- Maula, Terhi (författare)
- Department of Biochemistry, University of Turku, FI-20014 Turku, Finland
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- Bao, Kai (författare)
- Karolinska Institutet
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- Lindholm, Mark (författare)
- Umeå universitet,Institutionen för odontologi,Aa-gruppen
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- Bostanci, Nagihan (författare)
- Karolinska Institutet
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- Oscarsson, Jan (författare)
- Umeå universitet,Institutionen för odontologi,Aa-gruppen
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- Ihalin, Riikka (författare)
- Department of Biochemistry, University of Turku, FI-20014 Turku, Finland
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- Johansson, Anders, 1955- (författare)
- Umeå universitet,Institutionen för odontologi,Aa-gruppen
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(creator_code:org_t)
- 2019-11-06
- 2019
- Engelska.
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Ingår i: Pathogens. - Basel : MDPI. - 2076-0817. ; 8:4
- Relaterad länk:
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https://doi.org/10.3...
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https://umu.diva-por... (primary) (Raw object)
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https://www.mdpi.com...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Aggregatibacter actinomycetemcomitans is a periodontal pathogen colonizing the oral cavity of a large proportion of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade inflammation. Because of the large genetic diversity within the species, both harmless and highly virulent genotypes of the bacterium have emerged. The oral condition and age, as well as the geographic origin of the individual, influence the risk to be colonized by a virulent genotype of the bacterium. In the present review, the virulence and pathogenicity properties of A. actinomycetemcomitans will be addressed.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
Nyckelord
- Aggregatibacter actinomycetemcomitans
- biofilm
- cytokine binding factors
- cytolethal distending toxin
- horizontal gene transfer
- leukotoxin
- lipopolysaccharides
- outer membrane vesicles
- proteomic
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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