Sökning: id:"swepub:oai:DiVA.org:umu-173494" >
Target protection a...
Target protection as a key antibiotic resistance mechanism
-
Wilson, Daniel N. (författare)
-
- Hauryliuk, Vasili, 1980- (författare)
- Umeå universitet,Institutionen för molekylärbiologi (Medicinska fakulteten),Institute of Technology, Tartu University, Tartu, Estonia
-
- Atkinson, Gemma C. (författare)
- Umeå universitet,Institutionen för molekylärbiologi (Medicinska fakulteten)
-
visa fler...
-
O'Neill, Alex J. (författare)
-
visa färre...
-
(creator_code:org_t)
- 2020-06-25
- 2020
- Engelska.
-
Ingår i: Nature Reviews Microbiology. - : Nature Publishing Group. - 1740-1526 .- 1740-1534. ; 18:11, s. 637-648
- Relaterad länk:
-
https://eprints.whit...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Antibiotic resistance is mediated through several distinct mechanisms, most of which are relatively well understood and the clinical importance of which has long been recognized. Until very recently, neither of these statements was readily applicable to the class of resistance mechanism known as target protection, a phenomenon whereby a resistance protein physically associates with an antibiotic target to rescue it from antibiotic-mediated inhibition. In this Review, we summarize recent progress in understanding the nature and importance of target protection. In particular, we describe the molecular basis of the known target protection systems, emphasizing that target protection does not involve a single, uniform mechanism but is instead brought about in several mechanistically distinct ways.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Mikrobiologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Microbiology in the medical area (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
Hitta via bibliotek
Till lärosätets databas