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Prevalence of Aggre...
Prevalence of Aggregatibacter actinomycetemcomitans and Periodontal Findings among 14 to 15-Year Old Danish Adolescents : A Descriptive Cross-Sectional Study
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- Birkeholm Jensen, Anne (författare)
- Aarhus University, Denmark
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- Isidor, Flemming (författare)
- Aarhus University, Denmark
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- Lund, Marianne (författare)
- Aarhus University Denmark
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- Væth, Michael (författare)
- Aarhus University, Denmark
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- Johansson, Anders, 1955- (författare)
- Umeå universitet,Institutionen för odontologi,Aa-gruppen
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- Lauritsen, Niels Nørskov (författare)
- Aarhus University, Denmark
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- Haubek, Dorte (författare)
- Aarhus University, Denmark
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(creator_code:org_t)
- 2020-12-16
- 2020
- Engelska.
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Ingår i: Pathogens. - Basel : MDPI. - 2076-0817. ; 9:12
- Relaterad länk:
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https://doi.org/10.3...
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https://umu.diva-por... (primary) (Raw object)
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https://www.mdpi.com...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- Aggregatibacter actinomycetemcomitans (Aa) is a keystone pathogen associated with periodontitis in adolescents. The knowledge on the prevalence of Aa and periodontitis among adolescents in Northern Europe is sparse. A total of 525 14- to 15-year-old adolescents from the municipality of Aarhus, Denmark, underwent a full-mouth clinical examination. Plaque score (PS), bleeding on probing (BOP), probing pocket depth (PPD), and clinical attachment loss (CAL) were recorded. Subgingival plaque samples (SPS) and stimulated saliva samples (SSS) were collected and analyzed for the presence of JP2 and non-JP2 genotypes of Aa using real-time PCR. A total of 70 (13.3%) individuals were positive for Aa, with 17 found in SPS, 19 in SSS, and 35 in both. The highly leukotoxic JP2 genotype of Aa was not detected. The individuals positive for Aa in both SPS and SSS had poorer periodontal outcomes (PPD and CAL) than individuals without Aa and individuals carrying Aa in either SPS or SSS only. In conclusion, 13% of 14- to 15-year-old Danish adolescents were positive for Aa, and the presence of Aa in both SPS and SSS was associated with poorer periodontal outcomes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- A. actinomycetemcomitans
- JP2 genotype
- leukotoxin
- periodontal outcome
- periodontitis
- saliva sample
- subgingival plaque sample
- mikrobiologi
- Microbiology
- odontologi
- Odontology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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