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Probiotics for the management of pediatric gastrointestinal disorders : position paper of the ESPGHAN special interest group on gut microbiota and modifications

Szajewska, Hania (författare)
From the Department of Paediatrics, Medical University of Warsaw, Warsaw, Poland
Berni Canani, Roberto (författare)
Department of Translational Medical Science - Section of Paediatrics. University of Naples Federico II, Naples, Italy
Domellöf, Magnus, 1963- (författare)
Umeå universitet,Pediatrik
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Guarino, Alfredo (författare)
Department of Translational Medical Science - Section of Paediatrics. University of Naples Federico II, Naples, Italy
Hojsak, Iva (författare)
the Children's Hospital Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia, University J.J. Strossmayer School of Medicine Osijek, Osijek, Croatia
Indrio, Flavia (författare)
Department of Medical and Surgical Science Pediatric Section, University of Foggia, Foggia, Italy
Lo Vecchio, Andrea (författare)
Department of Translational Medical Science - Section of Paediatrics. University of Naples Federico II, Naples, Italy
Mihatsch, Walter A. (författare)
Ulm University, Ulm, Germany
Mosca, Alexis (författare)
Department of Pediatric Gastroenterology and Nutrition, Hopital Robert Debré, Assistance Publique Hopitaux de Paris, Paris, France
Orel, Rok (författare)
Department of Gastroenterology, Hepatology and Nutrition, University Medical Centre Ljubljana, University Children's Hospital Ljubljana, Ljubljana, Slovenia
Salvatore, Silvia (författare)
Department of Pediatrics, "F. Del Ponte" Hospital, University of Insubria, Varese, Italy
Shamir, Raanan (författare)
Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel
van den Akker, Chris H P (författare)
University of Amsterdam and Vrije Universiteit Amsterdam, Emma Children's Hospital, Paediatrics - Neonatology, Amsterdam Reproduction & Development, Amsterdam, Netherlands
van Goudoever, Johannes B. (författare)
University of Amsterdam and Vrije Universiteit Amsterdam, Emma Children's Hospital, Paediatrics - Neonatology, Amsterdam Reproduction & Development, Amsterdam, Netherlands
Vandenplas, Yvan (författare)
UZ Brussel, Vrije Universiteit Brussel, the KidZ Health Castle, Brussels, Belgium
Weizman, Zvi (författare)
Faculty of Health Sciences, Ben-Gurion University, Beer-Sheva, Israel
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From the Department of Paediatrics, Medical University of Warsaw, Warsaw, Poland Department of Translational Medical Science - Section of Paediatrics University of Naples Federico II, Naples, Italy (creator_code:org_t)
Lippincott Williams & Wilkins, 2023
2023
Engelska.
Ingår i: Journal of Pediatric Gastroenterology and Nutrition - JPGN. - : Lippincott Williams & Wilkins. - 0277-2116 .- 1536-4801. ; 76:2, s. 232-247
Relaterad länk:
https://urn.kb.se/re...
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https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • BACKGROUND: Probiotics, defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host, are widely used despite uncertainty regarding their efficacy and discordant recommendations about their use. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Special Interest Group on Gut Microbiota and Modifications provides updated recommendations for the use of probiotics for the management of selected pediatric gastrointestinal disorders.METHODS: All systematic reviews and/or meta-analyses, as well as subsequently published randomized controlled trials (RCTs) (until December 2021), that compared the use of probiotics in all delivery vehicles and formulations, at any dose, with no probiotic (ie, placebo or no treatment), were eligible for inclusion. The recommendations were formulated only if at least 2 RCTs on a similar well-defined probiotic strain were available. The modified Delphi process was used to establish consensus on the recommendations.RESULTS: Recommendations for the use of specific probiotic strains were made for the management of acute gastroenteritis, prevention of antibiotic-associated diarrhea, nosocomial diarrhea and necrotizing enterocolitis, management of Helicobacter pylori infection, and management of functional abdominal pain disorders and infant colic.CONCLUSIONS: Despite evidence to support the use of specific probiotics in some clinical situations, further studies confirming the effect(s) and defining the type, dose, and timing of probiotics are still often required. The use of probiotics with no documented health benefits should be discouraged.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)

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