SwePub
Sök i LIBRIS databas

  Utökad sökning

id:"swepub:oai:DiVA.org:umu-218178"
 

Sökning: id:"swepub:oai:DiVA.org:umu-218178" > Synthesis and chara...

Synthesis and characterization of a carbon nanotube−dendron series for efficient sirna delivery

Herrero, M. Antonia (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
Toma, Francesca M. (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
Al-Jamal, Khuloud T. (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
visa fler...
Kostarelos, Kostas (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
Bianco, Alberto (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
Da Ros, Tatiana (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
Bano, Fouzia (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
Casalis, Loredana (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
Scoles, Giacinto (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
Prato, Maurizio (författare)
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, U.K., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021...
visa färre...
Center of Excellence for Nanostructured Materials, Department of Pharmaceutical Sciences, and INSTM, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy, Departamento de Química Orgánica, Facultad de Química, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain, SISSA, 34014 Trieste, Italy, Nanomedicine Laboratory, Centre for Drug Delivery Research, The School of Pharmacy, University of London, London WC1N 1AX, UK., CNRS, Institut de Biologie Moléculaire et Cellulaire, UPR9021... (creator_code:org_t)
2009-06-25
2009
Engelska.
Ingår i: Journal of the American Chemical Society. - : American Chemical Society (ACS). - 0002-7863 .- 1520-5126. ; 131:28, s. 9843-9848
Relaterad länk:
https://urn.kb.se/re...
visa fler...
https://doi.org/10.1...
visa färre...
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • A new series of dendron-functionalized multiwalled carbon nanotube (MWNT) derivatives, characterized by the presence of numerous positively charged tetraalkyl ammonium salts at the periphery of the dendron, has been synthesized. The positive charges on the MWNT surface, coupled with the unique ability of carbon nanotubes (CNTs) to penetrate cell membranes, make the new derivatives potentially ideal vectors for siRNA delivery. Using a fluorescently labeled, noncoding siRNA sequence, we demonstrate that cytoplasmic delivery of the nucleic acid is remarkably increased throughout the different dendron generations. The work reported here highlights the fact that dendron-functionalized CNTs can be rationally designed as efficient carriers of siRNA that can eventually lead to gene silencing.

Ämnesord

NATURVETENSKAP  -- Kemi -- Materialkemi (hsv//swe)
NATURAL SCIENCES  -- Chemical Sciences -- Materials Chemistry (hsv//eng)
NATURVETENSKAP  -- Kemi -- Organisk kemi (hsv//swe)
NATURAL SCIENCES  -- Chemical Sciences -- Organic Chemistry (hsv//eng)

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy