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Associations of lon...
Associations of long-term exposure to air pollution and greenness with incidence of chronic obstructive pulmonary disease in Northern Europe : The Life-GAP project
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- Xu, Shanshan (författare)
- Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
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- Marcon, Alessandro (författare)
- Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy
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- Bertelsen, Randi Jacobsen (författare)
- Department of Clinical Science, University of Bergen, Bergen, Norway
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- Benediktsdottir, Bryndis (författare)
- Department of Respiratory Medicine and Sleep, Landspitali – the National University Hospital of Iceland, Reykjavik, Iceland; University of Iceland, Medical Faculty, Iceland
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- Brandt, Jørgen (författare)
- Department of Environmental Science, Aarhus University, Roskilde, Denmark
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- Frohn, Lise Marie (författare)
- Department of Environmental Science, Aarhus University, Roskilde, Denmark
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- Geels, Camilla (författare)
- Department of Environmental Science, Aarhus University, Roskilde, Denmark
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- Gislason, Thorarinn (författare)
- Department of Respiratory Medicine and Sleep, Landspitali – the National University Hospital of Iceland, Reykjavik, Iceland; University of Iceland, Medical Faculty, Iceland
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- Heinrich, Joachim (författare)
- Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany; Allergy and Lung Health Unit, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia
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- Holm, Mathias (författare)
- Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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- Janson, Christer (författare)
- Department of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden
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- Markevych, Iana (författare)
- Institute of Psychology, Jagiellonian University, Krakow, Poland; Health and Quality of Life in a Green and Sustainable Environment”, Strategic Research and Innovation Program for the Development of MU – Plovdiv, Medical University of Plovdiv, Plovdiv, Bulgaria; Environmental Health Division, Research Institute at Medical University of Plovdiv, Medical University of Plovdiv, Plovdiv, Bulgaria
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- Modig, Lars (författare)
- Umeå universitet,Avdelningen för hållbar hälsa
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- Orru, Hans (författare)
- Department of Public Health, Institute of Family Medicine and Public Health, Faculty of Medicine, University of Tartu, Tartu, Estonia
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- Schlünssen, Vivi (författare)
- Department of Public Health, Research unit for Environment Occupation and Health, Danish Ramazzini Center, Aarhus University, Aarhus, Denmark
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- Sigsgaard, Torben (författare)
- Department of Public Health, Research unit for Environment Occupation and Health, Danish Ramazzini Center, Aarhus University, Aarhus, Denmark
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- Johannessen, Ane (författare)
- Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway
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(creator_code:org_t)
- Elsevier, 2024
- 2024
- Engelska.
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Ingår i: Environmental Research. - : Elsevier. - 0013-9351 .- 1096-0953. ; 257
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Background: Prolonged exposure to air pollution has been linked to adverse respiratory health, yet the evidence concerning its association with chronic obstructive pulmonary disease (COPD) is inconsistent. The evidence of a greenness effect on chronic respiratory diseases is limited.Objective: This study aimed to investigate the association between long-term exposure to particulate matter (PM2.5 and PM10), black carbon (BC), nitrogen dioxide (NO2), ozone (O3) and greenness (as measured by the normalized difference vegetation index - NDVI) and incidence of self-reported chronic bronchitis or COPD (CB/COPD).Methods: We analyzed data from 5355 adults from 7 centers participating in the Respiratory Health in Northern Europe (RHINE) study. Mean exposures to air pollution and greenness were assessed at available residential addresses in 1990, 2000 and 2010 using air dispersion models and satellite data, respectively. Poisson regression with log person-time as an offset was employed to analyze the association between air pollution, greenness, and CB/COPD incidence, adjusting for confounders.Results: Overall, there were 328 incident cases of CB/COPD during 2010–2023. Despite wide statistical uncertainty, we found a trend for a positive association between NO2 exposure and CB/COPD incidence, with incidence rate ratios (IRRs) per 10 μg/m³ difference ranging between 1.13 (95% CI: 0.90–1.41) in 1990 and 1.18 (95% CI: 0.96–1.45) in 2000. O3 showed a tendency for inverse association with CB/COPD incidence (IRR from 0.84 (95% CI: 0.66–1.07) in 2000 to 0.88 (95% CI: 0.69–1.14) in 2010. No consistent association was found between PM, BC and greenness with CB/COPD incidence across different exposure time windows.Conclusion: Consistent with prior research, our study suggests that individuals exposed to higher concentrations of NO2 may face an elevated risk of developing COPD, although evidence remains inconclusive. Greenness was not associated with CB/COPD incidence, while O3 showed a tendency for an inverse association with the outcome.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Chronic bronchitis
- COPD
- Environmental epidemiology
- Green space
- Public health
- Respiratory health
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Xu, Shanshan
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Marcon, Alessand ...
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Bertelsen, Randi ...
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Benediktsdottir, ...
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Brandt, Jørgen
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Frohn, Lise Mari ...
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Geels, Camilla
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Gislason, Thorar ...
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Heinrich, Joachi ...
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Holm, Mathias
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Janson, Christer
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Markevych, Iana
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Modig, Lars
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Orru, Hans
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Schlünssen, Vivi
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Sigsgaard, Torbe ...
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Johannessen, Ane
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