Sökning: id:"swepub:oai:DiVA.org:umu-57677" >
Challenges for synt...
Challenges for synthesising data in a network of registries for systemic Psoriasis therapies
-
Ormerod, AD (författare)
-
Augustin, M (författare)
-
Baker, C (författare)
-
visa fler...
-
Chosidow, O (författare)
-
Cohen, AD (författare)
-
Dam, TN (författare)
-
Garcia-Doval, I (författare)
-
Lecluse, LL (författare)
-
- Schmitt-Egenolf, Marcus (författare)
- Umeå universitet,Dermatologi och venereologi
-
Spuls, PI (författare)
-
Watson, KD (författare)
-
Naldi, L (författare)
-
visa färre...
-
(creator_code:org_t)
- 2012-06-01
- 2012
- Engelska.
-
Ingår i: Dermatology. - : S. Karger. - 1018-8665 .- 1421-9832. ; 224:3, s. 236-243
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Background: Large disease registries are the preferred method to assess long-term treatment safety. If psoriasis registries collaborate in a network, their power to assess safety is increased.Objective: To identify heterogeneity in psoriasis registries and methodological challenges for synthesising the data they provide.Methods: We surveyed the registries in PSONET and identified and addressed the challenges to collaborative analysis for the network in several round table meetings.Results: Eight out of 10 registries had a prospective comparator cohort with similar disease characteristics but not on biologics. Registries differed in the coding and validation or follow-up of adverse events and in the way they sampled their population. Fifteen challenges to registries collaborating were identified in the areas of operational governance, structural conduct, bias and analysis.Conclusions: Participation in PSONET, a network of psoriasis registries, helps identify and solve common issues, enhancing the individual registries, and provides larger sets of more powerful safety data in a diverse population. Challenges to interpreting data collectively include heterogeneity in sampling, variable penetration of biologics and compatibility of different datasets.Copyright (c) 2012 S. Karger AG, Basel
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Nyckelord
- Biologics
- Methodology
- Psoriasis
- Registry
- Research network
- Systemic therapy
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Ormerod, AD
-
Augustin, M
-
Baker, C
-
Chosidow, O
-
Cohen, AD
-
Dam, TN
-
visa fler...
-
Garcia-Doval, I
-
Lecluse, LL
-
Schmitt-Egenolf, ...
-
Spuls, PI
-
Watson, KD
-
Naldi, L
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Dermatologi och ...
- Artiklar i publikationen
-
Dermatology
- Av lärosätet
-
Umeå universitet