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Tumour characterist...
Tumour characteristics and surgical treatment of renal cell carcinoma in Sweden 2005-2010 : a population-based study from the National Swedish Kidney Cancer Register
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Thorstenson, Andreas (författare)
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Bergman, Martin, 1985 (författare)
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Scherman-Plogell, Ann-Helen (författare)
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Hosseinnia, Soheila (författare)
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- Ljungberg, Börje (författare)
- Umeå universitet,Urologi och andrologi,Njurcancer
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- Adolfsson, Jan (författare)
- Karolinska Institutet
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Lundstam, Sven (författare)
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(creator_code:org_t)
- 2014-03-25
- 2014
- Engelska.
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Ingår i: Scandinavian journal of urology. - Abingdon : Taylor & Francis. - 2168-1805 .- 2168-1813. ; 48:3, s. 231-238
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://research.cha...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Objective. Tumour characteristics, preoperative work-up and surgical treatment in patients diagnosed with renal cell carcinoma (RCC) between 2005 and 2010, and changes over time were studied in a national population-based cohort. Material and methods. The National Swedish Kidney Cancer Register (NSKCR) contains information on histopathology, Fuhrman grade and clinical stage at presentation, and on the preoperative work-up and surgical treatment of patients with RCC. Between 2005 and 2010, 5553 RCC patients were registered in the NSKCR, 99% of those registered in the National Cancer Registry. Results. During the study period the mean tumour size decreased from 70 to 64 mm (p = 0.024) and the frequency of metastatic RCC decreased from 22% to 15% (p < 0.001). The use of preoperative chest computed tomography increased from 59% to 84%. In total, 4229 (76%) patients were treated with curative intent, 3453 (82%) underwent radical nephrectomy, 606 (14%) partial nephrectomy (PN) and 170 (4%) cryotherapy or radiofrequency ablation. In tumours up to 4 cm, PN was performed in 33% of the surgically treated patients. PN irrespective of size increased from 8% to 20% and laparoscopic nephrectomy increased from 6% to 17% during the period. In patients with metastatic RCC, 55% underwent cytoreductive nephrectomy. Conclusions. The NSKCR explores population-based data on the clinical handling of patients with RCC. This study, between 2005 and 2010, shows significant decrease in tumour size and metastatic RCC at presentation, a more complete preoperative work-up, and significantly increased use of PN and laparoscopic nephrectomy in Sweden.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- distant metastasis
- lymph-node metastasis
- population-based
- renal cell carcinoma
- survival
- tumour category
- tumour size
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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