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False-reactive micr...
False-reactive microbiologic screening test results in Swedish blood donors - How big is the problem? : A survey among blood centers and deferred donors
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- Tynell, Elsa (författare)
- Karolinska Institutet
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- Norda, Rut (författare)
- Uppsala universitet,Institutionen för onkologi, radiologi och klinisk immunologi
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- Ekermo, Bengt (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Transfusionsmedicin,Klinisk immunologi och transfusionsmedicin
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- Sanner, Margareta (författare)
- Uppsala universitet,Hälso- och sjukvårdsforskning,Health Services Research
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Andersson, Sören (författare)
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- Björkman, Anders (författare)
- Karolinska Institutet
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(creator_code:org_t)
- Wiley, 2007
- 2007
- Engelska.
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Ingår i: Transfusion. - : Wiley. - 0041-1132 .- 1537-2995. ; 47:1, s. 80-89
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Screening of blood donors for markers of transfusion-transmissible infectious agents leads to a varying number of false-reactive test results and sometimes thereby temporary or permanent deferral of donors and also to loss of collected units. STUDY DESIGN AND METHODS: Data on false-reactive screening test results in 2002 and 2003 were collected from 19 blood centers in Sweden. A questionnaire was sent to donors deferred because of false-reactive screening test results to investigate their perception of the information and their reaction to the deferral. RESULTS: Testing of 21,189 samples from new donors and 423,543 donations from regular and/or repeat donors produced 1,059 false-reactive test results, mostly from hepatitis C virus antibody testing, and 299 deferrals. Six different human immunodeficiency virus tests led to between 0.02 and 0.2 percent false-reactive results. The deferral rate varied considerably between different counties. Of 204 deferred donors contacted, 180 (88%) answered the questionnaire. More than 80 percent were worried about their test results and worry was more common among those who did not feel sufficiently informed. CONCLUSION: The results imply that there is a need for a more standardized approach to the screening of blood donors and donations with the aim of minimizing the number of false-reactive screening test results. They also emphasize the importance of appropriate information and support to deferred donors.
Nyckelord
- Blood donor
- Screening test
- Transfusion
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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