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Adolescent alcohol consumption : Biomarkers PEth and FAEE in relation to interview and questionnaire data
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- Comasco, Erika (författare)
- Uppsala universitet,Institutionen för neurovetenskap,Centrum för klinisk forskning, Västerås,Uppsala Univ, Pharmacol Unit, Dept Neurosci, BMC, S-75124 Uppsala, Sweden.;Uppsala Univ, Clin Res Ctr, Cent Hosp, Vasteras, Sweden.,Department of Neuroscience, Unit of Pharmacology, Uppsala University, Box 593, 751 24 Uppsala, Sweden, Centre for Clinical Research, Uppsala University, Central Hospital, Västerås, Sweden
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- Nordquist, Niklas (författare)
- Uppsala universitet,Institutionen för neurovetenskap,Uppsala Univ, Pharmacol Unit, Dept Neurosci, BMC, S-75124 Uppsala, Sweden.,Department of Neuroscience, Unit of Pharmacology, Uppsala University, Box 593, 751 24 Uppsala, Sweden, Section of Pharmacology, Department of Neuroscience, Uppsala University, Uppsala, Sweden
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- Leppert, Jerzy (författare)
- Uppsala universitet,Institutionen för neurovetenskap,Centrum för klinisk forskning, Västerås,Uppsala Univ, Pharmacol Unit, Dept Neurosci, BMC, S-75124 Uppsala, Sweden.,Department of Neuroscience, Unit of Pharmacology, Uppsala University, Box 593, 751 24 Uppsala, Sweden, Centre for Clinical Research, Uppsala University, Central Hospital, Västerås, Sweden
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- ALCOHOL RES DOCUMENTATION INC CENT ALCOHOL STUD RUTGERS UNIV, 2009
- 2009
- Engelska.
- Ingår i: Journal of Studies on Alcohol and Drugs. - : ALCOHOL RES DOCUMENTATION INC CENT ALCOHOL STUD RUTGERS UNIV. - 1937-1888 .- 1938-4114. ; 70:5, s. 797-804
- Tidskriftsartikel (refereegranskat)
Abstract
Ämnesord
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- OBJECTIVE The aim of this study was to investigate the congruence of biomarkers, questionnaires, and interviews as instruments to assess adolescent alcohol consumption. METHOD The methodology used was a cross-sectional study with a randomized sample. Four different methods were used to estimate high adolescent alcohol consumption. The concordance of the results was investigated. Surveys were performed, and biological specimens were collected at all schools in the county of Västmanland, Sweden, in 2001. Eighty-one boys and 119 girls from a population of 16- and 19-year-old adolescents were randomly selected from quartiles of volunteers representing various degrees of psychosocial risk behaviors. Using a questionnaire (for a 1-hour session) and in-depth interviews, subjects were assessed regarding their alcohol-use habits. Blood and hair samples were analyzed for phosphatidylethanol (PEth) and fatty acid ethyl esters (FAEEs), respectively. RESULTS High alcohol consumption was underreported in the questionnaire compared with the interviews. PEth and FAEE analyses weakly confirmed the self-reports, and the results of the two biochemical tests did not overlap. The PEth blood test was the most specific but the least sensitive, whereas the FAEE hair test revealed low specificity and an overrepresentation of positive results in girls. CONCLUSIONS The expected higher self-report of high alcohol consumption by interview rather than by questionnaire was confirmed partly because of the influence of a bogus pipeline procedure. The absence of overlap between PEth and FAEE results and their poor agreement with self-reports suggested that biomarkers are unsuitable as screening tools for alcohol consumption in adolescents.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- MEDICINE
- MEDICIN
- Farmakologi
- Pharmacology
- TECHNOLOGY
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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- Journal of Studies on Alcohol and Drugs (Sök värdpublikationen i LIBRIS)
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- Nilsson, Kent W.
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