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Melt electrospinnin...
Melt electrospinning of polycaprolactone and its blends with poly(ethylene glycol)
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Detta, Nicola (författare)
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Brown, Toby D. (författare)
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- Edin, Fredrik K. (författare)
- Uppsala universitet,Institutionen för biologisk grundutbildning
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Albrecht, Krystyna (författare)
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Chiellini, Federica (författare)
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Chiellini, Emo (författare)
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Dalton, Paul D. (författare)
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Hutmacher, Dietmar W. (författare)
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(creator_code:org_t)
- 2010-10-19
- 2010
- Engelska.
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Ingår i: Polymer international. - : Wiley. - 0959-8103 .- 1097-0126. ; 59:11, s. 1558-1562
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Melt electrospinning is one aspect of electrospinning with relatively little published literature, although the technique avoids solvent accumulation and/or toxicity which is favoured in certain applications In the study reported, we melt-electrospun blends of poly(epsilon-caprolactone) (PCL) and an amphiphilic diblock copolymer consisting of poly(ethylene glycol) and PCL segments (PEG-block PCL) A custom-made electrospinning apparatus was built and various combinations of instrument parameters such as voltage and polymer feeding rate were investigated Pure PEG-block-PCL copolymer melt electrospinning did not result in consistent and uniform fibres due to the low molecular weight, while blends of PCL and PEG-block-PCL, for some parameter combinations and certain weight ratios of the two components, were able to produce continuous fibres significantly thinner (average diameter of ca 2 mu m) compared to pure PCL The PCL fibres obtained had average diameters ranging from 6 to 33 mu m and meshes were uniform for the lowest voltage employed while mesh uniformity decreased when the voltage was increased This approach shows that PCL and blends of PEG block-PCL and PCL can be readily processed by melt electrospinning to obtain fibrous meshes with varied average diameters and morphologies that are of interest for tissue engineering purposes.
Ämnesord
- NATURVETENSKAP -- Kemi -- Polymerkemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Polymer Chemistry (hsv//eng)
Nyckelord
- electrospinning
- amphiphilic polymer
- block copolymer
- tissue engineering
- Polymer chemistry
- Polymerkemi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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