Sensitive Detection of Spores Using Volume-Amplified Magnetic Nanobeads

• A magnetic-nanobead-based, substrate-free method for the sensitive detection of spores in an immunoassay format is presented. The method is shown to detect Bacillus globigii spores, the non-pathogenic simulant of Bacillus anthracis, with a limit-of-detection of 50 spores with a reaction time of 135 min. The study shows the versatility of magnetic nanobeads for detection of biological molecules other than DNA.

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Nanoteknik (hsv//swe)

ENGINEERING AND TECHNOLOGY  -- Nano-technology (hsv//eng)

Nyckelord

biosensors

immunoassays

magnetic particles

spores

nanobeads

TECHNOLOGY

TEKNIKVETENSKAP

Engineering Science with specialization in Nanotechnology and Functional Materials

Teknisk fysik med inriktning mot nanoteknologi och funktionella material

Engineering Science with specialization in Solid State Physics

Teknisk fysik med inriktning mot fasta tillståndets fysik

Publikations- och innehållstyp

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