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The Impact of Cigar...
The Impact of Cigarette Smoking on Asthma : A Population-Based International Cohort Study
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Cerveri, Isa (författare)
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Cazzoletti, Lucia (författare)
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Corsico, Angelo G (författare)
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Marcon, Alessandro (författare)
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Niniano, Rosanna (författare)
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Grosso, Amelia (författare)
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Ronzoni, Vanessa (författare)
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Accordini, Simone (författare)
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- Janson, Christer (författare)
- Uppsala universitet,Lungmedicin och allergologi
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Pin, Isabelle (författare)
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Siroux, Valerie (författare)
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de Marco, Roberto (författare)
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(creator_code:org_t)
- 2012-01-26
- 2012
- Engelska.
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Ingår i: International Archives of Allergy and Immunology. - : S. Karger AG. - 1018-2438 .- 1423-0097. ; 158:2, s. 175-183
- Relaterad länk:
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https://www.karger.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Background: The prevalence rates of smoking in subjects with asthma have frequently been reported as similar to those in the general population; however, available data are not up-to-date. There is only limited and somewhat conflicting information on the long-term effects of smoking on health outcomes among population-based cohorts of subjects with asthma. We aimed to investigate changes in smoking habits and their effects on forced expiratory volume in 1 s (FEV(1)) in subjects with asthma in comparison with the rest of the population, focusing on the healthy smoker effect. Methods: We studied 9,092 subjects without asthma and 1,045 with asthma at baseline who participated in both the European Community Respiratory Health Survey I (20-44 years old in 1991-1993) and II (1999-2002). Results: At follow-up, smoking was significantly less frequent among subjects with asthma than in the rest of the population (26 vs. 31%; p < 0.001). Subjects with asthma who were already ex-smokers at the beginning of the follow-up in the 1990s had the highest mean asthma score (number of reported asthma-like symptoms, range 0-5), probably as a result of the healthy smoker effect (2.80 vs. 2.44 in never smokers, 2.19 in quitters and 2.24 in smokers; p < 0.001). The influence of smoking on FEV(1) decline did not depend on asthma status. Smokers had the highest proportion of subjects with chronic cough/phlegm (p < 0.01). Conclusion: One out of 4 subjects with asthma continues smoking and reports significantly more chronic cough and phlegm than never smokers and ex-smokers. This stresses the importance of smoking cessation in all patients with asthma, even in those with less severe asthma.
Nyckelord
- Asthma
- Cigarette smoking
- Epidemiology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
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Cerveri, Isa
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Cazzoletti, Luci ...
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Corsico, Angelo ...
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Marcon, Alessand ...
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Niniano, Rosanna
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Grosso, Amelia
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visa fler...
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Ronzoni, Vanessa
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Accordini, Simon ...
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Janson, Christer
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Pin, Isabelle
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Siroux, Valerie
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de Marco, Robert ...
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visa färre...
- Artiklar i publikationen
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International Ar ...
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Uppsala universitet