Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer.

Nyckelord

Adenocarcinoma

Breast Neoplasms

Carcinoma; Hepatocellular

Choriocarcinoma

Chromosomes

DNA Methylation

Enhancer Elements (Genetics)/*physiology

Enzyme Inhibitors/pharmacology

Female

Gene Expression Regulation; Neoplastic/drug effects/physiology

Histone Deacetylases/*antagonists & inhibitors/metabolism

Humans

Hydroxamic Acids/pharmacology

Introns

Liver Neoplasms

Mutagenesis/physiology

Promoter Regions (Genetics)/*physiology

Proto-Oncogene Proteins c-sis/*genetics

Rhabdomyosarcoma

Transcription; Genetic/drug effects/physiology

Tumor Cells; Cultured

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)