Sökning: id:"swepub:oai:DiVA.org:uu-255041" >
The chorda tympani ...
The chorda tympani degenerates during chronic otitis media : an electron microscopy study
-
- Berling, Katarina (författare)
- Uppsala universitet,Centrum för klinisk forskning, Västerås
-
- Mannstrom, Paula (författare)
- Karolinska Institutet
-
Ulfendahl, Mats (författare)
-
visa fler...
-
- Lillieström, Niklas Danckwardt (författare)
- Uppsala universitet,Öron-, näs- och halssjukdomar
-
- Von Unge, Magnus (författare)
- Uppsala universitet,Centrum för klinisk forskning, Västerås
-
visa färre...
-
(creator_code:org_t)
- 2015-02-26
- 2015
- Engelska.
-
Ingår i: Acta Oto-Laryngologica. - : Informa UK Limited. - 0001-6489 .- 1651-2251. ; 135:6, s. 542-548
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.3...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- Conclusion: Chorda tympani nerve specimens from ears with chronic inflammatory middle ear disease exhibit structural signs of degeneration. These correlate well with taste disturbance. Simultaneously, they exhibit signs of regeneration, which may explain the ability for taste recovery. Objectives: The chorda tympani, the major taste nerve, runs uncovered through the middle ear cavity. This situation exposes it to various forms of middle ear pathology. A difference has been noticed regarding taste symptoms pre- and postoperatively between inflammatory and non-inflammatory diseases. The present study aimed to investigate ultrastructural changes of chorda tympani in different forms of inflammatory middle ear disease, such as chronic suppurative otitis media and cholesteatoma, as compared with normal. Methods: Five chorda tympani specimens were collected from healthy middle ears of patients subjected to surgery for acoustic neuroma, to be used as normal controls, and five from middle ears with chronic otitis media or cholesteatoma, where the nerve could not be saved during the operation. Light and electron microscopy were performed. Results: For all five nerves from diseased ears, microscopy showed a higher percentage of axon and myelin sheath degeneration than in the normal controls. Furthermore, three of the five also exhibited sprouting.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Oto-rhino-laryngologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Otorhinolaryngology (hsv//eng)
Nyckelord
- Taste
- otosurgery
- degeneration
- sprouting
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas