Mild and Robust Redox-Neutral Pd/C-Catalyzed Lignol -O-4 Bond Cleavage Through a Low-Energy-Barrier Pathway

• A Pd/C catalyzed redox neutral CO bond cleavage of 2-aryloxy-1-arylethanols has been developed. The reactions are carried out at 80 degrees C, in air, using a green solvent system to yield the aryl ketones in near quantitative yields. Addition of catalytic amounts of a hydrogen source to the reaction mixture activates the catalyst to proceed through a low energy barrier pathway. Initial studies support a transfer hydrogenolysis reaction mechanism that proceeds through an initial dehydrogenation followed by an enol adsorption to Pd/C and a reductive CO bond cleavage.

Ämnesord

NATURVETENSKAP  -- Kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences (hsv//eng)

Nyckelord

heterogeneous catalysis

lignin

palladium

reaction mechanisms

transfer hydrogenolysis

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