THE SYNTHESIS AND REACTIVITY OF NEW 2-(N,N-DIISOPROPYLAMINO)-3-METHYLSULFONYL-1,3,2-BENZOXAZAPHOSPHOLES - THE UTILITY OF THE 5-CHLORO ANALOG IN THE ONE-POT SYNTHESIS OF OLIGOTHIOPHOSPHATES - [AP(S)PPA, AP(S)PPPA, PPP5'A2'P(S)5'A, M(7)GP(S)PPA, AP(S)PPPP,

• The synthesis of 2-(N,N-diisopropylamino)-2-3-dihydro-3-methylsulfonyl-1,3,2- benzoxazaphospholes 22, 23 and 24 is reported. Their reactivities have been investigated using a variety of acid catalyst under conditions normally employed in phosphoramidite c

Nyckelord

SOLID-PHASE SYNTHESIS; PHOSPHORYLATING REAGENTS; DESICCANT EFFICIENCY; DEOXYNUCLEOSIDE PHOSPHORAMIDITES; OLIGONUCLEOTIDE SYNTHESIS; OLIGORIBONUCLEOTIDES; CONVENIENT; PHOSPHORUS; TETRAZOLE; SOLVENT

Publikations- och innehållstyp

vet (ämneskategori)

art (ämneskategori)