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Anastomotic breakin...
Anastomotic breaking strength and healing of anastomoses in rat intestine with and without chronic radiation damage.
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Jahnson, S (författare)
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Graf, W (författare)
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Rikner, G (författare)
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visa fler...
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Gerdin, Bengt, 1947- (författare)
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visa färre...
- 1995
- 1995
- Engelska.
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Ingår i: European Journal of Surgery. - 1102-4151 .- 1741-9271. ; 161:6, s. 425-30
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- OBJECTIVE: To assess the influence of chronic radiation damage on anastomotic healing in the small bowel in rats.DESIGN: Controlled laboratory study.SETTING: University hospital, Sweden.MATERIAL: 90 male Sprague-Dawley rats.INTERVENTIONS: A short segment of the distal ileum was exteriorised and irradiated with a single dose (experimental group, n = 45) or exposed only (control group, n = 45). Twenty weeks later resection and anastomosis were done within this segment using 7/0 polypropylene.MAIN OUTCOME MEASURES: The anastomotic breaking strength, the amount of perianastomotic hydroxyproline, and the number of anastomotic complications.RESULTS: The breaking strength and the amount of perianastomotic hydroxyproline were higher in the irradiated than in the non-irradiated group. In contrast, anastomotic complications were significantly more common in irradiated animals.CONCLUSION: Anastomotic complications in irradiated intestine are not related to the amount of perianastomotic collagen or to breaking strength.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Andra medicinska och farmaceutiska grundvetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Other Basic Medicine (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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