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Brief Report :
Brief Report : Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs.
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- Isaksson, Johan (author)
- Karolinska Institutet,Uppsala universitet,Barn- och ungdomspsykiatri,Karolinska Inst, Ctr Neurodev Disorders, Dept Womens & Childrens Hlth, Pediat Neuropsychiat Unit,Karolinska Inst KIND, Stockholm, Sweden.; Stockholm Cty Council, Ctr Psychiat Res, Stockholm, Sweden
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- Pettersson, Erik (author)
- Karolinska Institutet
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- Kostrzewa, Elzbieta (author)
- Karolinska Inst, Ctr Neurodev Disorders, Dept Womens & Childrens Hlth, Pediat Neuropsychiat Unit,Karolinska Inst KIND, Stockholm, Sweden
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- Diaz Heijtz, Rochellys (author)
- Karolinska Institutet
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- Bölte, Sven (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2017-05-23
- 2017
- English.
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In: Journal of autism and developmental disorders. - : Springer Science and Business Media LLC. - 0162-3257 .- 1573-3432. ; 47:8, s. 2621-2627
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Autism spectrum disorder (ASD) has been associated with gastrointestinal (GI) problems, but the nature of this association is unclear. Parents to siblings, concordant or discordant for ASD (N = 217), participated in a web survey covering mother's weight gain during pregnancy, maternal viral/bacterial infection and use of antibiotics, duration of breastfeeding, mode of delivery, birth weight and child GI problems. ASD was associated with GI problems and perinatal environmental risk, based on a summation of maternal infection and antibiotic use during pregnancy and/or the breastfeeding period. The association between GI problems and ASD remained within the sibling pairs (β = 1.23; p < .001) in the adjusted model. Our results indicate non-shared environmental effects on the ASD/GI association, but none of the factors examined explained the link.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- Autism spectrum disorder
- Breastfeeding
- Cesarean section
- Gastrointestinal problems
- Infections
- Siblings
Publication and Content Type
- ref (subject category)
- art (subject category)
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