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Patterns of African...
Patterns of African and Asian admixture in the Afrikaner population of South Africa
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- Hollfelder, Nina (författare)
- Uppsala universitet,Människans evolution
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- Erasmus, Johannes Christoff (författare)
- Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria, South Africa
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- Hammarén, Rickard (författare)
- Uppsala universitet,Människans evolution
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- Vicente, Mário (författare)
- Uppsala universitet,Människans evolution
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- Jakobsson, Mattias (författare)
- Uppsala universitet,Science for Life Laboratory, SciLifeLab,Människans evolution,Palaeo-Research Institute, University of Johannesburg, Auckland Park, South Africa
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- Greeff, Jaco M. (författare)
- Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria, South Africa
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- Schlebusch, Carina, 1977- (författare)
- Uppsala universitet,Människans evolution,Science for Life Laboratory, SciLifeLab,Department of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria, South Africa
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(creator_code:org_t)
- 2020-02-24
- 2020
- Engelska.
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Ingår i: BMC Biology. - : Springer Science and Business Media LLC. - 1741-7007. ; 18:1
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://bmcbiol.biom...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- BACKGROUND: The Afrikaner population of South Africa is the descendants of European colonists who started to colonize the Cape of Good Hope in the 1600s. In the early days of the colony, mixed unions between European males and non-European females gave rise to admixed children who later became incorporated into either the Afrikaner or the Coloured populations of South Africa. Differences in ancestry, social class, culture, sex ratio and geographic structure led to distinct and characteristic admixture patterns in the Afrikaner and Coloured populations. The Afrikaner population has a predominant European composition, whereas the Coloured population has more diverse ancestries. Genealogical records previously estimated the contribution of non-Europeans into the Afrikaners to be between 5.5 and 7.2%. RESULTS: To investigate the genetic ancestry of the Afrikaner population today (11-13 generations after initial colonization), we genotyped approximately five million genome-wide markers in 77 Afrikaner individuals and compared their genotypes to populations across the world to determine parental source populations and admixture proportions. We found that the majority of Afrikaner ancestry (average 95.3%) came from European populations (specifically northwestern European populations), but that almost all Afrikaners had admixture from non-Europeans. The non-European admixture originated mostly from people who were brought to South Africa as slaves and, to a lesser extent, from local Khoe-San groups. Furthermore, despite a potentially small founding population, there is no sign of a recent bottleneck in the Afrikaner compared to other European populations. Admixture amongst diverse groups from Europe and elsewhere during early colonial times might have counterbalanced the effects of a small founding population. CONCLUSIONS: While Afrikaners have an ancestry predominantly from northwestern Europe, non-European admixture signals are ubiquitous in the Afrikaner population. Interesting patterns and similarities could be observed between genealogical predictions and our genetic inferences. Afrikaners today have comparable inbreeding levels to current-day European populations.
Ämnesord
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
Nyckelord
- Afrikaner
- South Africa
- Admixture
- Slave trade
- Colonial times
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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