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Estimated glomerula...
Estimated glomerular filtration rate and functional status among older people : A systematic review
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- Corsonello, Andrea (author)
- Karolinska Institutet,INRCA Ancona, Ancona, Fermo & Cosenza, Italy
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- Roller-Wirnsberger, Regina (author)
- Med Univ Graz, Dept Internal Med, Graz, Austria
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- Di Rosa, Mirko (author)
- INRCA Ancona, Ancona, Fermo & Cosenza, Italy
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- Fabbietti, Paolo (author)
- INRCA Ancona, Ancona, Fermo & Cosenza, Italy
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- Wirnsberger, Gerhard (author)
- Med Univ Graz, Dept Internal Med, Graz, Austria
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- Kostka, Tomasz (author)
- Med Univ Lodz, Dept Geriatr, Hlth Ageing Res Ctr, Lodz, Poland
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- Guligowska, Agnieszka (author)
- Med Univ Lodz, Dept Geriatr, Hlth Ageing Res Ctr, Lodz, Poland
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- Tap, Lisanne (author)
- Erasmus Univ, Med Ctr Rotterdam, Dept Internal Med, Sect Geriatr Med, Rotterdam, Netherlands
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- Mattace-Raso, Francesco (author)
- Erasmus Univ, Med Ctr Rotterdam, Dept Internal Med, Sect Geriatr Med, Rotterdam, Netherlands
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- Gil, Pedro (author)
- Hosp Clin San Carlos, Dept Geriatr Med, Madrid, Spain
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- Guardado-Fuentes, Lara (author)
- Hosp Clin San Carlos, Dept Geriatr Med, Madrid, Spain
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- Meltzer, Itshak (author)
- Ben Gurion Univ Negev, Fac Hlth Sci, Recanati Sch Community Hlth Profess, Beer Sheva, Israel
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- Yehoshua, Ilan (author)
- Maccabi Healthcare Serv Southern Reg, Tel Aviv, Israel
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- Artzi-Medevdik, Rada (author)
- Ben Gurion Univ Negev, Fac Hlth Sci, Recanati Sch Community Hlth Profess, Beer Sheva, Israel;Maccabi Healthcare Serv Southern Reg, Tel Aviv, Israel
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- Formiga, Francesc (author)
- Bellvitge Univ Hosp IDIBELL, Internal Med Dept, Geriatr Unit, Barcelona, Spain;Bellvitge Univ Hosp IDIBELL, Nephrol Dept, Barcelona, Spain
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- Moreno-Gonzalez, Rafael (author)
- Bellvitge Univ Hosp IDIBELL, Internal Med Dept, Geriatr Unit, Barcelona, Spain;Bellvitge Univ Hosp IDIBELL, Nephrol Dept, Barcelona, Spain
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- Weingart, Christian (author)
- Friedrich Alexander Univ Erlangen Nurnberg, Krankenhaus Barmherzige Bruder Regensburg, Dept Gen Internal Med & Geriatr, Erlangen, Germany;Friedrich Alexander Univ Erlangen Nurnberg, Inst Biomed Aging, Erlangen, Germany
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- Freiberger, Ellen (author)
- Friedrich Alexander Univ Erlangen Nurnberg, Krankenhaus Barmherzige Bruder Regensburg, Dept Gen Internal Med & Geriatr, Erlangen, Germany;Friedrich Alexander Univ Erlangen Nurnberg, Inst Biomed Aging, Erlangen, Germany
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- Ärnlöv, Johan (author)
- Högskolan Dalarna,Karolinska Institutet,Uppsala universitet,Institutionen för medicinska vetenskaper,Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden,Medicinsk vetenskap,Uppsala University; Karolinska Institutet
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- Carlsson, Axel C (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Karolinska Inst, Care Sci & Soc, Dept Neurobiol, Div Family Med, Huddinge, Sweden
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- Lattanzio, Fabrizia (author)
- INRCA Ancona, Ancona, Fermo & Cosenza, Italy
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(creator_code:org_t)
- Elsevier, 2018
- 2018
- English.
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In: European journal of internal medicine. - : Elsevier. - 0953-6205 .- 1879-0828. ; 56, s. 39-48
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Abstract
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- Background: The association between chronic kidney disease (CKD) and functional status may change as a function of the equation used to estimate glomerular filtration rate (eGFR). We reviewed the predictive value of different eGFR equations in regard to frailty and disability outcomes. Methods: We searched Pubmed from inception to March 2018 for studies investigating the association between eGFR and self-reported and/or objective measures of frailty or disability. Cross-sectional and longitudinal studies were separately analysed. Results: We included 16 studies, one of which reporting both cross-sectional and longitudinal data. Three out of 7 cross-sectional studies compared different eGFR equations in regard to their association with functional status: two studies showed that cystatin C-based, but not creatinine-based eGFR may be associated with hand-grip strength or frailty; another study showed that two different creatinine-based eGFR equations may be similarly associated with disability. Four out of 10 longitudinal studies provided comparative data: two studies reported similar association with disability for different creatinine-based eGFR equations; one study showed that creatinine-based eGFR was not associated with frailty, but a not significant trend for association was observed with cystatin C-based eGFR; one study showed that cystatin C-based but not creatinine-based eGFR may predict incident mobility disability, while both methods may predict gait speed decline. High heterogeneity was observed in regard to confounders included in reviewed studies. None of them included the most recently published equations. Conclusion: Available data do not support the superiority of one of the eGFR equations in terms of measuring or predicting functional decline.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Gerontologi, medicinsk/hälsovetenskaplig inriktning (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Gerontology, specialising in Medical and Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- Estimated glomerular filtration rate (eGFR)
- Creatinine
- Cystatin C
- Frailty
- Disability
- Hälsa och välfärd
Publication and Content Type
- ref (subject category)
- for (subject category)
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- By the author/editor
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Corsonello, Andr ...
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Roller-Wirnsberg ...
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Di Rosa, Mirko
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Fabbietti, Paolo
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Wirnsberger, Ger ...
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Kostka, Tomasz
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show more...
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Guligowska, Agni ...
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Tap, Lisanne
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Mattace-Raso, Fr ...
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Gil, Pedro
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Guardado-Fuentes ...
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Meltzer, Itshak
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Yehoshua, Ilan
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Artzi-Medevdik, ...
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Formiga, Frances ...
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Moreno-Gonzalez, ...
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Weingart, Christ ...
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Freiberger, Elle ...
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Ärnlöv, Johan
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Carlsson, Axel C
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Lattanzio, Fabri ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Other Medical an ...
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and Gerontology spec ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
- Articles in the publication
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European journal ...
- By the university
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Uppsala University
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Karolinska Institutet
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Högskolan Dalarna