Downsizing proteolytic digestion and analysis using dispenser-aided sample handling and nanovial matrix-assisted laser/desorption ionization-target arrays

• An efficient technique for enzymatic digestion of proteins in nanovial arrays and identification by peptide mass fingerprinting using matrix-assisted laser desorption/ionization (MALDI-MS) is presented in this work. Through dispensing of a protein solutio

Nyckelord

matrix-assisted laser desorption ionization-mass spectrometry; protein identification; on-target proteolytic digestion; nanovial array; silicon flow-through microdispenser; FLIGHT MASS-SPECTROMETRY; FLOW-THROUGH DISPENSER; CHIP-BASED NANOVIALS; PROTEIN ID

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