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The synthesis of deuterionucleosides
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- Foldesi, A (author)
- Uppsala universitet,Institutionen för bioorganisk kemi
- Trifonova, A (author)
- Kundu, MK (author)
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- Chattopadhyaya, J (author)
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- (creator_code:org_t)
- MARCEL DEKKER INC, 2000
- 2000
- English.
- In: NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS. - : MARCEL DEKKER INC. ; 19:10-12, s. 1615-1656
- Review (other academic/artistic)
Abstract
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- The synthesis of deuterionucleosides for site-specific incorporation into oligo-DNA or -RNA is herein reviewed for NMR or biological studies. The review covers the following aspects: (i) deuteration of the aglycone; (ii) single-site chemical deuteration o
Keyword
- ACID RELATED-COMPOUNDS; NUCLEAR-MAGNETIC-RESONANCE; HYDROGEN-DEUTERIUM EXCHANGE; HIGHLY DIASTEREOSELECTIVE SYNTHESIS; DEUTERATED HYDROXYMETHYL GROUP; LASER-RAMAN SPECTROSCOPY; PROCHIRAL C-5' PROTONS; ENZYMATIC-SYNTHESIS; NMR-SPECTROSCOPY; OLIGO-DNA
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