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Trends in age- and ...
Trends in age- and sex-adjusted body mass index and the prevalence of malnutrition in children with cancer over 42 months after diagnosis : a single-center cohort study
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- Aarnivala, Henri (författare)
- Univ Oulu, Oulu Univ Hosp, Dept Children & Adolescents, Kajaanintie 52, SF-90220 Oulu, Finland;Univ Oulu, PEDEGO Res Unit, Kajaanintie 52, SF-90220 Oulu, Finland
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- Pokka, Tytti (författare)
- Univ Oulu, Oulu Univ Hosp, Dept Children & Adolescents, Kajaanintie 52, SF-90220 Oulu, Finland;Univ Oulu, PEDEGO Res Unit, Kajaanintie 52, SF-90220 Oulu, Finland
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- Soininen, Riina (författare)
- Univ Oulu, Oulu Univ Hosp, Dept Children & Adolescents, Kajaanintie 52, SF-90220 Oulu, Finland;Univ Oulu, PEDEGO Res Unit, Kajaanintie 52, SF-90220 Oulu, Finland
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- Mottonen, Merja (författare)
- Univ Oulu, Oulu Univ Hosp, Dept Children & Adolescents, Kajaanintie 52, SF-90220 Oulu, Finland;Univ Oulu, PEDEGO Res Unit, Kajaanintie 52, SF-90220 Oulu, Finland
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- Harila-Saari, Arja (författare)
- Uppsala universitet,Barnneurologi/Barnonkologi
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- Niinimaki, Riitta (författare)
- Univ Oulu, Oulu Univ Hosp, Dept Children & Adolescents, Kajaanintie 52, SF-90220 Oulu, Finland;Univ Oulu, PEDEGO Res Unit, Kajaanintie 52, SF-90220 Oulu, Finland
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(creator_code:org_t)
- 2019-10-28
- 2020
- Engelska.
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Ingår i: European Journal of Pediatrics. - : SPRINGER. - 0340-6199 .- 1432-1076. ; 179:1, s. 91-98
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Abstract
Ämnesord
Stäng
- The adequate nutritional status of pediatric cancer patients is particularly important to enable them to cope with the demands of the disease and its treatment and to maintain normal growth. Malnutrition and obesity have both been associated with reduced survival and increased drug toxicity. We investigated trends in the age- and sex-adjusted body mass index (ISO-BMI) and the prevalence of malnutrition in a Finnish cohort of 139 consecutive children receiving chemotherapy for cancer, with a follow-up period of 42 months after diagnosis. In total, 28% (39/139) of the patients experienced malnutrition (ISO-BMI < 17 or > 10% weight loss), and 12% (16/139) had a nasogastric tube or underwent gastrostomy. Patients with acute or chronic myeloid leukemia (5/10), central nervous system (CNS) tumors (5/13), or solid tumors (13/31) most frequently suffered from malnutrition. There was a significant increase in the ISO-BMI of patients with acute lymphoblastic leukemia (ALL) (+ 2.1 kg/m(2)) and lymphomas (+ 2.4 kg/m(2)) during the first 6 months, and the ISO-BMI of patients with ALL remained higher at 42 months compared to baseline (+ 1.9 kg/m(2)). Conclusion: The cumulative incidence of malnutrition in Finnish pediatric cancer patients is comparable to that reported in other populations. The nutritional status of patients with acute myeloid leukemia, CNS tumors, or solid tumors should be monitored with extra care to facilitate early intervention in the case of impending malnutrition.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Nyckelord
- Body mass index
- Cancer
- Chemotherapy
- Child
- ISO-BMI
- Malnutrition
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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