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Split renal functio...
Split renal function after treatment of small renal masses : comparison between radiofrequency ablation and laparoscopic partial nephrectomy.
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- Acosta Ruiz, Vanessa, 1987- (författare)
- Uppsala universitet,Radiologi
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- Båtelsson, Sarah (författare)
- Uppsala universitet,Radiologi
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- Onkamo, Elina (författare)
- Uppsala universitet,Radiologi
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- Wernroth, Lisa (författare)
- Uppsala universitet,Molekylär epidemiologi
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- Nilsson, Thomas (författare)
- Uppsala universitet,Institutionen för medicinska vetenskaper
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- Lönnemark, Maria (författare)
- Uppsala universitet,Radiologi
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- Dahlman, Pär (författare)
- Uppsala universitet,Radiologi
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- Magnusson, Anders, 1947- (författare)
- Uppsala universitet,Radiologi
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(creator_code:org_t)
- 2020-09-10
- 2021
- Engelska.
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Ingår i: Acta Radiologica. - : Sage Publications. - 0284-1851 .- 1600-0455. ; 62:9, s. 1248-1256
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Radiofrequency ablation (RFA) and laparoscopic partial nephrectomy (LPN) are used to treat small renal masses (SRM; ≤4 cm), although there are conflicting results in the changes in creatinine and estimated glomerular filtration rate (eGFR) after treatment. On contrast-enhanced computed tomography (CE-CT) images, the quantity and quality of renal function can be evaluated by calculating the split renal function (SRF).PURPOSE: To compare renal function after RFA or LPN treatment of SRMs through evaluation of the SRF in the affected kidney.MATERIAL AND METHODS: Single T1a renal tumors successfully treated with RFA (n = 60) or LPN (n = 31) were retrospectively compared. The SRF was calculated on pre-treatment CE-CT images and the first follow-up exam after completed treatment. Serum creatinine and eGFR values were collected simultaneously. To compare renal function outcomes, Student's t-test and multivariable linear regression models (adjusted to RFA/LPN treatment, pre-treatment SRF/eGFR, BMI, age, tumor characteristics, and Charlson Comorbidity Index) were used.RESULTS: SRF was reduced in both groups, although reduction was greater in the LPN group (LPN -5.7%) than in the RFA group (RFA -3.5%; P = 0.013). After adjusted analysis, the LPN group still had greater SRF reduction (difference 3.2%, 95% confidence interval 1.3-1.5; P = 0.001). There was no difference between groups in the change of creatinine/eGFR after treatment.CONCLUSION: Both RFA and LPN are nephron-sparing when treating SRMs. However, in this series, reduction of SRF in the affected kidney was smaller after RFA, having a more favorable preservation of renal function than LPN.
Nyckelord
- Kidney
- ablation procedures
- computed tomography
- percutaneous
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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