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Million-year-old DN...
Million-year-old DNA sheds light on the genomic history of mammoths
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- van der Valk, Tom (författare)
- Naturhistoriska riksmuseet,Uppsala universitet,Beräkningsbiologi och bioinformatik,Science for Life Laboratory, SciLifeLab,Ctr Palaeogenet, Stockholm, Sweden; Swedish Museum Nat Hist, Dept Bioinformat & Genet, Stockholm, Sweden,Enheten för bioinformatik och genetik
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- Pečnerová, Patrícia (författare)
- Naturhistoriska riksmuseet,Stockholms universitet,Zoologiska institutionen,Swedish Museum of Natural History, Sweden; University of Copenhagen, Denmark,Swedish Museum Nat Hist, Dept Bioinformat & Genet, Stockholm, Sweden; Stockholm Univ, Dept Zool, Stockholm, Sweden; Univ Copenhagen, Sect Computat & RNA Biol, Dept Biol, Copenhagen, Denmark,Enheten för bioinformatik och genetik
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- Díez-del-Molino, David (författare)
- Naturhistoriska riksmuseet,Stockholms universitet,Zoologiska institutionen,Centre for Palaeogenetics, Sweden; Swedish Museum of Natural History, Sweden,Ctr Palaeogenet, Stockholm, Sweden; Swedish Museum Nat Hist, Dept Bioinformat & Genet, Stockholm, Sweden; Stockholm Univ, Dept Zool, Stockholm, Sweden,Enheten för bioinformatik och genetik
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visa fler...
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- Bergström, Anders (författare)
- Francis Crick Inst, London, England
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- Oppenheimer, Jonas (författare)
- Univ Calif Santa Cruz, Dept Biomol Engn, Santa Cruz, CA 95064 USA
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- Hartmann, Stefanie (författare)
- Univ Potsdam, Inst Biochem & Biol, Potsdam, Germany
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- Xenikoudakis, Georgios (författare)
- Univ Potsdam, Inst Biochem & Biol, Potsdam, Germany
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- Thomas, Jessica A. (författare)
- Univ Potsdam, Inst Biochem & Biol, Potsdam, Germany
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- Dehasque, Marianne (författare)
- Naturhistoriska riksmuseet,Stockholms universitet,Zoologiska institutionen,Centre for Palaeogenetics, Sweden; Swedish Museum of Natural History, Sweden,Ctr Palaeogenet, Stockholm, Sweden; Swedish Museum Nat Hist, Dept Bioinformat & Genet, Stockholm, Sweden; Stockholm Univ, Dept Zool, Stockholm, Sweden,Enheten för bioinformatik och genetik
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- Saglican, Ekin (författare)
- Middle East Tech Univ, Dept Biol Sci, Ankara, Turkey
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- Fidan, Fatma Rabia (författare)
- Middle East Tech Univ, Dept Biol Sci, Ankara, Turkey
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- Barnes, Ian (författare)
- Nat Hist Museum, Dept Earth Sci, London, England
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- Liu, Shanlin (författare)
- China Agr Univ, Coll Plant Protect, Beijing, Peoples R China
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- Somel, Mehmet (författare)
- Middle East Tech Univ, Dept Biol Sci, Ankara, Turkey
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- Heintzman, Peter D. (författare)
- UiT Arctic Univ Norway, Arctic Univ Museum Norway, Tromso, Norway
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- Nikolskiy, Pavel (författare)
- Russian Acad Sci, Geol Inst, Moscow, Russia
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- Shapiro, Beth (författare)
- Univ Calif Santa Cruz, Dept Ecol & Evolutionary Biol, Santa Cruz, CA 95064 USA; Univ Calif Santa Cruz, Howard Hughes Med Inst, Santa Cruz, CA 95064 USA
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- Skoglund, Pontus (författare)
- Francis Crick Inst, London, England
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- Hofreiter, Michael (författare)
- Univ Potsdam, Inst Biochem & Biol, Potsdam, Germany
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- Lister, Adrian M. (författare)
- Nat Hist Museum, Dept Earth Sci, London, England
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- Götherström, Anders (författare)
- Stockholms universitet,Institutionen för arkeologi och antikens kultur,Centre for Palaeogenetics, Sweden,Ctr Palaeogenet, Stockholm, Sweden; Stockholm Univ, Dept Archaeol & Class Studies, Stockholm, Sweden
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- Dalén, Love (författare)
- Naturhistoriska riksmuseet,Stockholms universitet,Zoologiska institutionen,Centre for Palaeogenetics, Sweden; Swedish Museum of Natural History, Sweden,Ctr Palaeogenet, Stockholm, Sweden; Swedish Museum Nat Hist, Dept Bioinformat & Genet, Stockholm, Sweden; Stockholm Univ, Dept Zool, Stockholm, Sweden,Enheten för bioinformatik och genetik
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(creator_code:org_t)
- 2021-02-17
- 2021
- Engelska.
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Ingår i: Nature. - : Springer Nature. - 0028-0836 .- 1476-4687. ; 591:7849, s. 265-269
- Relaterad länk:
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https://www.ncbi.nlm...
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visa fler...
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https://nrm.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Temporal genomic data hold great potential for studying evolutionary processes such as speciation. However, sampling across speciation events would, in many cases, require genomic time series that stretch well back into the Early Pleistocene subepoch. Although theoretical models suggest that DNA should survive on this timescale1, the oldest genomic data recovered so far are from a horse specimen dated to 780–560 thousand years ago2. Here we report the recovery of genome-wide data from three mammoth specimens dating to the Early and Middle Pleistocene subepochs, two of which are more than one million years old. We find that two distinct mammoth lineages were present in eastern Siberia during the Early Pleistocene. One of these lineages gave rise to the woolly mammoth and the other represents a previously unrecognized lineage that was ancestral to the first mammoths to colonize North America. Our analyses reveal that the Columbian mammoth of North America traces its ancestry to a Middle Pleistocene hybridization between these two lineages, with roughly equal admixture proportions. Finally, we show that the majority of protein-coding changes associated with cold adaptation in woolly mammoths were already present one million years ago. These findings highlight the potential of deep-time palaeogenomics to expand our understanding of speciation and long-term adaptive evolution.
Ämnesord
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
Nyckelord
- Diversity of life
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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van der Valk, To ...
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Pečnerová, Patrí ...
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Díez-del-Molino, ...
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Bergström, Ander ...
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Oppenheimer, Jon ...
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Hartmann, Stefan ...
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visa fler...
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Xenikoudakis, Ge ...
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Thomas, Jessica ...
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Dehasque, Marian ...
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Saglican, Ekin
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Fidan, Fatma Rab ...
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Barnes, Ian
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Liu, Shanlin
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Somel, Mehmet
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Heintzman, Peter ...
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Nikolskiy, Pavel
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Shapiro, Beth
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Skoglund, Pontus
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Hofreiter, Micha ...
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Lister, Adrian M ...
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Götherström, And ...
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Dalén, Love
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Uppsala universitet
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