The burden of atherosclerosis in Portugal

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The burden of atherosclerosis in Portugal

Costa, Joao (author): Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Fac Med, Lab Farmacol Clin & Terapeut, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Fac Med, Inst Med Mol, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.

Alarcao, Joana (author): Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.

Araujo, Francisco (author): Hosp Beatriz Angelo, Serv Med, Av Carlos Teixeira 3, P-2674514 Loures, Portugal.

Ascencao, Raquel (author): Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Fac Med, Inst Med Prevent, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Ctr Cardiovasc, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Ctr Acad Med Lisboa, Fac Med, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.

Caldeira, Daniel (author): Univ Lisbon, Fac Med, Lab Farmacol Clin & Terapeut, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Fac Med, Inst Med Mol, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Ctr Cardiovasc, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Ctr Acad Med Lisboa, Fac Med, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.

Fiorentino, Francesca (author): Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.

Gil, Victor (author): Hosp Lusiadas, Unidade Cardiovasc, R Abilio Mendes 12, P-1500458 Lisbon, Portugal.;Univ Lisbon, Ctr Cardiovasc, Fac Med, Dept Med, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Porto, Fac Med, Dept Med, Alameda Prof Hernani Monteiro, P-4200319 Porto, Portugal.

Gouveia, Miguel (author): Univ Catolica Portuguesa, Ctr Estudos Aplicados, Catolica Lisbon Sch Business & Econ, P-1649023 Lisbon, Portugal.

Lourenco, Francisco (author): Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.

Mello e Silva, Alberto (author): Soc Portuguesa Aterosclerose, Av Jose Malhoa 2, P-1070158 Lisbon, Portugal.

Sampaio, Filipa, PhD, 1985- (author): Uppsala universitet,Socialmedicin/CHAP,Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal

Carneiro, Antonio Vaz (author): Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Fac Med, Inst Saude Baseada Evidencia, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.

Borges, Margarida (author): Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Fac Med, Lab Farmacol Clin & Terapeut, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Ctr Hosp Lisboa Cent EPE, Unidade Farmacol Clin, Alameda Santo Antonio Capuchos, P-1169050 Lisbon, Portugal.

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Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal;Univ Lisbon, Fac Med, Lab Farmacol Clin & Terapeut, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal.;Univ Lisbon, Fac Med, Inst Med Mol, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal. Univ Lisbon, Fac Med, Ctr Estudos Med Baseada Evidencia CEMBE, Av Prof Egas Moniz, P-1649028 Lisbon, Portugal. (creator_code:org_t)

2020-09-18
2021
English.
In: European Heart Journal - Quality of Care and Clinical Outcomes. - : Oxford University Press. - 2058-5225 .- 2058-1742. ; 7:2, s. 154-162

Related links:: https://doi.org/10.1...; show more...; https://uu.diva-port... (primary) (Raw object); https://academic.oup...; https://urn.kb.se/re...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

Aims This article sought to estimate the burden of disease attributable to atherosclerosis in mainland Portugal in 2016.Methods and results The burden of atherosclerosis was measured in disability-adjusted life years following the latest 2010 Global Burden of Disease (GBD) methodology. Disability-adjusted life years were estimated as the sum of years of life lost (YLL) with years lived with disability (YLD). The following clinical manifestations of atherosclerosis were included: ischaemic heart disease (IHD) (including acute myocardial infarction, stable angina, and ischaemic heart failure), ischaemic cerebrovascular disease (ICVD), and peripheral arterial disease (PAD). Years of life lost were estimated based on all-cause mortality data for the Portuguese population and mortality due to IHD, ICVD, and PAD for the year 2016 sourced from national statistics. Standard life expectancy was sourced from the GBD study. Years lived with disability corresponded to the product of the number of prevalent cases by an average disability weight for all possible combinations of disease. Prevalence data for the different clinical manifestations of atherosclerosis were sourced from epidemiological studies. Disability weights were sourced from the published literature. In 2016, 15123 deaths were attributable to atherosclerosis, which corresponded to 14.3% of overall mortality in mainland Portugal. Disability-adjusted life years totalled 260943, 75% due to premature death (196438 YLL) and 25% due to disability (64505 YLD).Conclusion Atherosclerosis entails a high disease burden to society. A large part of this burden would be avoidable if evidence-based effective and cost-effective interventions targeting known risk factors, from prevention to treatment, were implemented.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Keyword

Atherosclerosis
Burden of disease
DALYs
Morbidity
Mortality
Portugal

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ref (subject category)
art (subject category)

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By the author/editor: Costa, Joao; Alarcao, Joana; Araujo, Francisc ...; Ascencao, Raquel; Caldeira, Daniel; Fiorentino, Fran ...; show more...; Gil, Victor; Gouveia, Miguel; Lourenco, Franci ...; Mello e Silva, A ...; Sampaio, Filipa, ...; Carneiro, Antoni ...; Borges, Margarid ...; show less...

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