Sökning: id:"swepub:oai:DiVA.org:uu-443192" >
Exploring the Antib...
Exploring the Antibiotic Resistance Burden in Livestock, Livestock Handlers and Their Non-Livestock Handling Contacts : A One Health Perspective
-
- Hickman, Rachel A. (författare)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
-
- Leangapichart, Thongpan (författare)
- Norwegian Vet Inst, Sect Anim Hlth & Food Safety, Oslo, Norway
-
- Lunha, Kamonwan (författare)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences,Swedish Univ Agr Sci, Dept Clin Sci, Uppsala, Sweden
-
visa fler...
-
- Jiwakanon, Jatesada (författare)
- Khon Kaen Univ, Res Grp Anim Hlth Technol, Fac Vet Med, Khon Kaen, Thailand,Khon Kaen University
-
- Angkititrakul, Sunpetch (författare)
- Khon Kaen Univ, Res Grp Anim Hlth Technol, Fac Vet Med, Khon Kaen, Thailand
-
- Magnusson, Ulf (författare)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences,Swedish Univ Agr Sci, Dept Clin Sci, Uppsala, Sweden
-
- Sunde, Marianne (författare)
- Norwegian Vet Inst, Sect Anim Hlth & Food Safety, Oslo, Norway
-
- Järhult, Josef D., 1975- (författare)
- Uppsala universitet,Infektionsmedicin
-
visa färre...
-
(creator_code:org_t)
-
- 2021-04-20
- 2021
- Engelska.
-
Ingår i: Frontiers in Microbiology. - : Frontiers Media S.A.. - 1664-302X. ; 12
- Relaterad länk:
-
https://doi.org/10.3...
-
visa fler...
-
https://uu.diva-port... (primary) (Raw object)
-
https://www.frontier...
-
https://pub.epsilon.... (primary) (Raw object) (free)
-
https://urn.kb.se/re...
-
https://doi.org/10.3...
-
https://res.slu.se/i...
-
visa färre...
Abstract
Ämnesord
Stäng
- Antibiotics are freqeuently used in the livestock sector in low- and middle-income countries for treatment, prophylaxis, and growth promotion. However, there is limited information into the zoonotic prevalence and dissemination patterns of antimicrobial resistance (AMR) within these environments. In this study we used pig farming in Thailand as a model to explore AMR; 156 pig farms were included, comprising of small-sized (<50 sows) and medium-sized (≥100 sows) farms, where bacterial isolates were selectively cultured from animal rectal and human fecal samples. Bacterial isolates were subjected to antimicrobial susceptibility testing (AST), and whole-genome sequencing. Our results indicate extensive zoonotic sharing of antibiotic resistance genes (ARGs) by horizontal gene transfer. Resistance to multiple antibiotics was observed with higher prevalence in medium-scale farms. Zoonotic transmission of colistin resistance in small-scale farms had a dissemination gradient from pigs to handlers to non-livestock contacts. We highly recommend reducing the antimicrobial use in animals’ feeds and medications, especially the last resort drug colistin.
Ämnesord
- NATURVETENSKAP -- Biologi -- Mikrobiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Microbiology (hsv//eng)
Nyckelord
- one-health approach
- antibiotic resistance
- zoonotic transmission
- E. coli
- livestock
- pigs
- meat-production
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas