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Neurological manife...
Neurological manifestations of COVID-19 : A comprehensive literature review and discussion of mechanisms
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- Johansson, Anton (författare)
- Uppsala universitet,Schiöth: Funktionell farmakologi
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- Mohamed, Mohamed S. (författare)
- Uppsala universitet,Schiöth: Funktionell farmakologi
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- Moulin, Thiago (författare)
- Uppsala universitet,Schiöth: Funktionell farmakologi
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- Schiöth, Helgi B. (författare)
- Uppsala universitet,Schiöth: Funktionell farmakologi,Sechenov First Moscow State Med Univ, Inst Translat Med & Biotechnol, Moscow, Russia.
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(creator_code:org_t)
- Elsevier, 2021
- 2021
- Engelska.
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Ingår i: Journal of Neuroimmunology. - : Elsevier. - 0165-5728 .- 1872-8421. ; 358
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Several neurological symptoms and complications have been described in association with COVID-19, such as anosmia, ageusia, encephalitis and Guillain-Barre ' syndrome. Here, we review the literature describing SARSCoV-2-induced neurological manifestations and provide a comprehensive discussion of proposed mechanisms underlying the neurological pathophysiology. First, we analyse the neuroinvasiveness potential of the coronavirus family based on previous SARS-CoV-1 studies. Then, we describe the current evidence on COVID-19induced nervous tissue damage, including processes behind brain vasculopathy and cytokine storm. We also discuss in detail anosmia and Guillain-Barre ' syndrome. Finally, we provide a summarised timeline of the main findings in the field. Future perspectives are presented, and suggestions of further investigations to clarify how SARS-COV-2 can affect the CNS.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Nyckelord
- COVID-19
- Anosmia
- Encephalitis
- Cytokine storm
Publikations- och innehållstyp
- ref (ämneskategori)
- for (ämneskategori)
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