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MAS :
MAS : Standalone Microwave Resonator to Assess Muscle Quality
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- Mattsson, Viktor (författare)
- Uppsala universitet,Fasta tillståndets elektronik
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- Ackermans, Leanne L. G. C. (författare)
- Maastricht Univ, Dept Traumatol, Med Ctr, NL-6229 HX Maastricht, Netherlands.
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- Mandal, Bappaditya (författare)
- Uppsala universitet,Fasta tillståndets elektronik
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- Perez, Mauricio D. (författare)
- Uppsala universitet,Fasta tillståndets elektronik
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- Vesseur, Maud A. M. (författare)
- Maastricht Univ, Dept Traumatol, Med Ctr, NL-6229 HX Maastricht, Netherlands.
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- Meaney, Paul (författare)
- Dartmouth Coll, Thayer Sch Engn, Hanover, NH 03755 USA.
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- Ten Bosch, Jan A. (författare)
- Maastricht Univ, Dept Traumatol, Med Ctr, NL-6229 HX Maastricht, Netherlands.
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- Blokhuis, Taco J. (författare)
- Maastricht Univ, Dept Traumatol, Med Ctr, NL-6229 HX Maastricht, Netherlands.
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- Augustine, Robin, 1982- (författare)
- Uppsala universitet,Fasta tillståndets elektronik
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(creator_code:org_t)
- 2021-08-14
- 2021
- Engelska.
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Ingår i: Sensors. - : MDPI. - 1424-8220. ; 21:16
- Relaterad länk:
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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https://www.mdpi.com...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- Microwave-based sensing for tissue analysis is recently gaining interest due to advantages such as non-ionizing radiation and non-invasiveness. We have developed a set of transmission sensors for microwave-based real-time sensing to quantify muscle mass and quality. In connection, we verified the sensors by 3D simulations, tested them in a laboratory on a homogeneous three-layer tissue model, and collected pilot clinical data in 20 patients and 25 healthy volunteers. This report focuses on initial sensor designs for the Muscle Analyzer System (MAS), their simulation, laboratory trials and clinical trials followed by developing three new sensors and their performance comparison. In the clinical studies, correlation studies were done to compare MAS performance with other clinical standards, specifically the skeletal muscle index, for muscle mass quantification. The results showed limited signal penetration depth for the Split Ring Resonator (SRR) sensor. New sensors were designed incorporating Substrate Integrated Waveguides (SIW) and a bandstop filter to overcome this problem. The sensors were validated through 3D simulations in which they showed increased penetration depth through tissue when compared to the SRR. The second-generation sensors offer higher penetration depth which will improve clinical data collection and validation. The bandstop filter is fabricated and studied in a group of volunteers, showing more reliable data that warrants further continuation of this development.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
Nyckelord
- muscle quality
- sarcopenia
- microwave sensing
- bandstop filter
- substrate integrated waveguides
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- art (ämneskategori)
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