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The associations be...
The associations between maternal BMI and gestational weight gain and health outcomes in offspring at age 1 and 7 years
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- Chiavaroli, Valentina (författare)
- Univ Auckland, Liggins Inst, Auckland, New Zealand.;Pescara Publ Hosp, Neonatal Intens Care Unit, Pescara, Italy.
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- Hopkins, Sarah A. (författare)
- Univ Auckland, Liggins Inst, Auckland, New Zealand.;Univ Auckland, Fac Med & Hlth Sci, Dept Psychol Med, Auckland, New Zealand.
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- Biggs, Janene B. (författare)
- Univ Auckland, Liggins Inst, Auckland, New Zealand.
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- Rodrigues, Raquel O. (författare)
- Univ Auckland, Liggins Inst, Auckland, New Zealand.;Univ Kentucky, Coll Publ Hlth, Dept Hlth Behav & Soc, Lexington, KY USA.
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- Seneviratne, Sumudu N. (författare)
- Univ Auckland, Liggins Inst, Auckland, New Zealand.;Univ Colombo, Fac Med, Dept Paediat, Colombo, Sri Lanka.
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- Baldi, James C. (författare)
- Univ Otago, Dunedin Sch Med, Dept Med, Dunedin, New Zealand.
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- McCowan, Lesley M. E. (författare)
- Univ Auckland, Fac Med & Hlth Sci, Dept Obstet & Gynaecol, Auckland, New Zealand.
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- Cutfield, Wayne S. (författare)
- Univ Auckland, Liggins Inst, Auckland, New Zealand.;Univ Auckland, Better Start Natl Sci Challenge, Auckland, New Zealand.
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- Hofman, Paul L. (författare)
- Univ Auckland, Liggins Inst, Auckland, New Zealand.
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- Derraik, José G. B. (författare)
- Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning,Univ Auckland, Liggins Inst, Auckland, New Zealand.;Uppsala Univ, Dept Womens & Childrens Hlth, Uppsala, Sweden.;Chiang Mai Univ, Res Inst Hlth Sci, Chiang Mai, Thailand.
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Univ Auckland, Liggins Inst, Auckland, New Zealand;Pescara Publ Hosp, Neonatal Intens Care Unit, Pescara, Italy. Univ Auckland, Liggins Inst, Auckland, New Zealand.;Univ Auckland, Fac Med & Hlth Sci, Dept Psychol Med, Auckland, New Zealand. (creator_code:org_t)
- 2021-10-21
- 2021
- Engelska.
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Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 11:1
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://www.nature.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- In secondary analyses of a randomised controlled trial of exercise during pregnancy, we examined associations between mid-pregnancy maternal body mass index (BMI) and excessive gestational weight gain (GWG) with offspring health. Follow-up data were available on 57 mother-child pairs at 1-year and 52 pairs at 7-year follow-ups. Clinical assessments included body composition and fasting blood tests. At age 1 year, increased maternal BMI in mid-gestation was associated with greater weight standard deviation scores (SDS) in the offspring (p = 0.035), with no observed associations for excessive GWG. At age 7 years, greater maternal BMI was associated with increased weight SDS (p < 0.001), BMI SDS (p = 0.005), and total body fat percentage (p = 0.037) in their children. Irrespective of maternal BMI, children born to mothers with excessive GWG had greater abdominal adiposity (p = 0.043) and less favourable lipid profile (lower HDL-C and higher triglycerides). At 7 years, maternal BMI and excessive GWG had compounded adverse associations with offspring adiposity. Compared to offspring of mothers with overweight/obesity plus excessive GWG, children of normal-weight mothers with adequate and excessive GWG were 0.97 and 0.64 SDS lighter (p = 0.002 and p = 0.014, respectively), and 0.98 and 0.63 SDS leaner (p = 0.001 and p = 0.014, respectively). Both greater maternal BMI in mid-pregnancy and excessive GWG were independently associated with increased adiposity in offspring at 7 years.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
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Chiavaroli, Vale ...
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Hopkins, Sarah A ...
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Biggs, Janene B.
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Rodrigues, Raque ...
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Seneviratne, Sum ...
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Baldi, James C.
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McCowan, Lesley ...
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Cutfield, Wayne ...
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Hofman, Paul L.
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Derraik, José G. ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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Uppsala universitet