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Variations in the m...
Variations in the management of diffuse low-grade gliomas : A Scandinavian multicenter study
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- Munkvold, Bodil Karoline Ravn (författare)
- Norwegian Univ Sci & Technol, Fac Med & Hlth Sci, Dept Neuromed & Movement Sci, NTNU, Trondheim, Norway.,Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway
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- Solheim, Ole (författare)
- Norwegian Univ Sci & Technol, Fac Med & Hlth Sci, Dept Neuromed & Movement Sci, NTNU, Trondheim, Norway.;Trondheim Reg & Univ Hosp, Dept Neurosurg, St Olavs Hosp, Trondheim, Norway.,Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway;Department of Neurosurgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
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- Bartek, Jiri (författare)
- Karolinska Institutet,Karolinska Institute,Copenhagen University Hospital,Karolinska University Hospital
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- Corell, Alba (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
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- de Dios, Eddie (författare)
- Uppsala University,Uppsala universitet,Institutionen för neurovetenskap,Sahlgrens Univ Hosp, Dept Neurosurg, Gothenburg, Sweden,Department of Neurosurgery, Sahlgrenska University Hospital, Gothenburg, Sweden;Department of Neuroscience, Uppsala University, Uppsala, Sweden,Sahlgrens Univ Hosp, Sweden; Uppsala Univ, Sweden
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- Gulati, Sasha (författare)
- Norwegian Univ Sci & Technol, Fac Med & Hlth Sci, Dept Neuromed & Movement Sci, NTNU, Trondheim, Norway.;Trondheim Reg & Univ Hosp, Dept Neurosurg, St Olavs Hosp, Trondheim, Norway.,Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway;Department of Neurosurgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
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- Helseth, Eirik (författare)
- Oslo Univ Hosp, Dept Neurosurg, Oslo, Norway.;Univ Oslo, Fac Med, Inst Clin Med, Oslo, Norway.,Department of Neurosurgery, Oslo University Hospital, Oslo, Norway;Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
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- Holmgren, Klas (författare)
- Umeå University,Umeå universitet,Neurovetenskaper,Department of Neurosurgery, University Hospital of Northern Sweden, Umeå, Sweden,Umeå Univ, Dept Clin Sci, Neurosci, Umeå, Sweden.;Univ Hosp Northern Sweden, Dept Neurosurg, Umeå, Sweden.,Norrland University Hospital
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- Jensdottir, Margret (författare)
- Karolinska Univ Hosp, Dept Neurosurg, Stockholm, Sweden.,Department of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden
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- Lundborg, Mina (författare)
- Oslo Univ Hosp, Dept Neurosurg, Oslo, Norway.,Department of Neurosurgery, Oslo University Hospital, Oslo, Norway
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- Mireles, Eduardo Erasmo Mendoza (författare)
- Oslo Univ Hosp, Dept Neurosurg, Oslo, Norway.,Department of Neurosurgery, Oslo University Hospital, Oslo, Norway
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- Mahesparan, Ruby (författare)
- Univ Bergen, Fac Med, Dept Clin Med, Bergen, Norway.;Haukeland Hosp, Dept Neurosurg, Bergen, Norway.,Department of Clinical Medicine, Faculty of Medicine, University of Bergen, Bergen, Norway;Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway
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- Tveiten, Oystein Vesterli (författare)
- Univ Bergen, Fac Med, Dept Clin Med, Bergen, Norway.;Haukeland Hosp, Dept Neurosurg, Bergen, Norway.,Department of Clinical Medicine, Faculty of Medicine, University of Bergen, Bergen, Norway;Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway
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- Milos, Peter (författare)
- Linköpings universitet,Avdelningen för neurobiologi,Medicinska fakulteten,Region Östergötland, Neurokirurgiska kliniken US,Linköping Univ Hosp, Dept Neurosurg, Linköping, Sweden.,Linköping University Hospital
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- Nittby Redebrandt, Henrietta (författare)
- Lund University,Lunds universitet,Neurokirurgi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rausinglaboratoriet i Lund - Tumörsektionen,Forskargrupper vid Lunds universitet,Neurosurgery,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Rausing laboratory of Lund - Tumor section,Lund University Research Groups,Skåne University Hospital
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- Pedersen, Lars Kjelsberg (författare)
- Univ Hosp North Norway, Dept Neurosurg, Tromso, Norway.,Department of Neurosurgery, University Hospital of North Norway, Tromsø, Norway
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- Ramm-Pettersen, Jon (författare)
- Oslo Univ Hosp, Dept Neurosurg, Oslo, Norway.,Department of Neurosurgery, Oslo University Hospital, Oslo, Norway
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- Sjöberg, Rickard L. (författare)
- Umeå University,Umeå universitet,Neurovetenskaper,Department of Neurosurgery, University Hospital of Northern Sweden, Umeå, Sweden,Umeå Univ, Dept Clin Sci, Neurosci, Umeå, Sweden.;Univ Hosp Northern Sweden, Dept Neurosurg, Umeå, Sweden.,Norrland University Hospital
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- Sjögren, Björn (författare)
- Linköping Univ Hosp, Dept Neurosurg, Linköping, Sweden.,Department of Neurosurgery, Linköping University Hospital, Sweden,Region Östergötland, Neurokirurgiska kliniken US
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- Sjavik, Kristin (författare)
- Univ Hosp North Norway, Dept Neurosurg, Tromso, Norway.,Department of Neurosurgery, University Hospital of North Norway, Tromsø, Norway
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- Smits, Anja (författare)
- Gothenburg University,Göteborgs universitet,Uppsala universitet,Landtblom: Neurovetenskap,Sahlgrens Acad, Inst Neurosci & Physiol, Gothenburg, Sweden,Institute of Neuroscience and Physiology, Sahlgrenska Academy, Gothenburg, Sweden;Department of Neuroscience, Uppsala University, Uppsala, Sweden,Sahlgrens Acad, Sweden; Uppsala Univ, Sweden,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
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- Tomasevic, Gregor (författare)
- Skane Univ Hosp, Dept Neurosurg, Lund, Sweden.,Department of Neurosurgery, Skåne University Hospital, Lund, Sweden
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- Vecchio, Tomás Gomez (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
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- Vik-Mo, Einar O. (författare)
- Oslo Univ Hosp, Dept Neurosurg, Oslo, Norway.;Univ Oslo, Fac Med, Inst Clin Med, Oslo, Norway.,Department of Neurosurgery, Oslo University Hospital, Oslo, Norway;Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway
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- Zetterling, Maria (författare)
- Uppsala University,Uppsala universitet,Enblad: Neurokirurgi,Uppsala Univ Hosp, Dept Neurosurg, Uppsala, Sweden,Department of Neuroscience, Uppsala University, Uppsala, Sweden;Department of Neurosurgery, Uppsala University Hospital, Uppsala, Sweden
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- Salvesen, Oyvind (författare)
- Norwegian Univ Sci & Technol, Fac Med & Hlth Sci, Dept Publ Hlth & Nursing, Trondheim, Norway.,Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
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- Jakola, Asgeir Store (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
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Tveiten, ØV (författare)
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Salvesen, Ø (författare)
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Norwegian Univ Sci & Technol, Fac Med & Hlth Sci, Dept Neuromed & Movement Sci, NTNU, Trondheim, Norway Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, NTNU, Trondheim, Norway (creator_code:org_t)
- 2021-09-04
- 2021
- Engelska.
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Ingår i: Neuro-Oncology Practice. - : Oxford University Press. - 2054-2577 .- 2054-2585. ; 8:6, s. 706-717
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Abstract
Ämnesord
Stäng
- Background. Early extensive surgery is a cornerstone in treatment of diffuse low-grade gliomas (DLGGs), and an additional survival benefit has been demonstrated from early radiochemotherapy in selected "high-risk" patients. Still, there are a number of controversies related to DLGG management. The objective of this multicenter population-based cohort study was to explore potential variations in diagnostic work-up and treatment between treating centers in 2 Scandinavian countries with similar public health care systems.Methods. Patients screened for inclusion underwent primary surgery of a histopathologically verified diffuse WHO grade II glioma in the time period 2012 through 2017. Clinical and radiological data were collected from medical records and locally conducted research projects, whereupon differences between countries and inter-hospital variations were explored.Results. A total of 642 patients were included (male:female ratio 1:4), and annual age-standardized incidence rates were 0.9 and 0.8 per 100 000 in Norway and Sweden, respectively. Considerable inter-hospital variations were observed in preoperative work-up, tumor diagnostics, surgical strategies, techniques for intraoperative guidance, as well as choice and timing of adjuvant therapy.Conclusions. Despite geographical population-based case selection, similar health care organizations, and existing guidelines, there were considerable variations in DLGG management. While some can be attributed to differences in clinical implementation of current scientific knowledge, some of the observed inter-hospital variations reflect controversies related to diagnostics and treatment. Quantification of these disparities renders possible identification of treatment patterns associated with better or worse outcomes and may thus represent a step toward more uniform evidence-based care.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
Nyckelord
- adjuvant
- chemotherapy
- diagnostic imaging
- glioma
- radiotherapy
- surgical oncology
- adjuvant
- chemotherapy
- diagnostic imaging
- glioma
- radiotherapy
- surgical oncology
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Munkvold, Bodil ...
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Solheim, Ole
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Bartek, Jiri
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Corell, Alba
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de Dios, Eddie
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Gulati, Sasha
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visa fler...
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Helseth, Eirik
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Holmgren, Klas
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Jensdottir, Marg ...
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Lundborg, Mina
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Mireles, Eduardo ...
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Mahesparan, Ruby
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Tveiten, Oystein ...
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Milos, Peter
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Nittby Redebrand ...
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Pedersen, Lars K ...
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Ramm-Pettersen, ...
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Sjöberg, Rickard ...
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Sjögren, Björn
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Sjavik, Kristin
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Smits, Anja
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Tomasevic, Grego ...
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Vecchio, Tomás G ...
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Vik-Mo, Einar O.
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Zetterling, Mari ...
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Salvesen, Oyvind
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Jakola, Asgeir S ...
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Tveiten, ØV
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Salvesen, Ø
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