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Short- and long-ter...
Short- and long-term mortality after deep sternal wound infection following cardiac surgery : experiences from
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- Kaspersen, Alexander Emil (författare)
- Aarhus Univ, Fac Hlth, Dept Clin Med, Aarhus, Denmark.;Aarhus Univ Hosp, Dept Cardiothorac & Vasc Surg, Aarhus, Denmark.
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- Nielsen, Susanne, 1969 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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- Orrason, Andri Wilberg (författare)
- Uppsala universitet,Urologkirurgi
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- Petursdottir, Astridur (författare)
- Landspitali Univ Hosp, Dept Cardiothorac Surg, Reykjavik, Iceland.
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- Sigurdsson, Martin Ingi (författare)
- Univ Iceland, Fac Med, Reykjavik, Iceland.;Landspitali Univ Hosp, Dept Anaesthesia & Intens Care, Reykjavik, Iceland.
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- Jeppsson, Anders, 1960 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
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- Gudbjartsson, Tomas (författare)
- Landspitali Univ Hosp, Dept Cardiothorac Surg, Reykjavik, Iceland.;Univ Iceland, Fac Med, Reykjavik, Iceland.
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Aarhus Univ, Fac Hlth, Dept Clin Med, Aarhus, Denmark;Aarhus Univ Hosp, Dept Cardiothorac & Vasc Surg, Aarhus, Denmark. Institutionen för medicin, avdelningen för molekylär och klinisk medicin (creator_code:org_t)
- 2021-02-24
- 2021
- Engelska.
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Ingår i: European Journal of Cardio-Thoracic Surgery. - : Oxford University Press. - 1010-7940 .- 1873-734X. ; 60:2, s. 233-241
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- OBJECTIVES: Deep sternal wound infection (DSWI) is a serious complication after open-heart surgery. We investigated the association between DSWI and short- and long-term all-cause mortality in a large well-defined nationwide population. METHODS: A retrospective, nationwide cohort study, which included 114676 consecutive patients who underwent coronary artery bypass grafting (CABG) and/or valve surgery from 1997 to 2015 in Sweden. Short- and long-term mortality was compared between DSWI patients and non-DSWI patients using propensity score inverse probability weighting adjustment based on patient characteristics and comorbidities. Median follow-up was 8.0 years (range 0-18.9). RESULTS: Altogether, 1516 patients (1.3%) developed DSWI, most commonly in patients undergoing combined CABG and valve surgery (2.1%). DSWI patients were older and had more disease burden than non-DSWI patients. The unadjusted cumulative mortality was higher in the DSWI group compared with the non-DSWI group at 90 days (7.9% vs 3.0%, P < 0.001) and at 1 year (12.8% vs 4.5%, P < 0.001). The adjusted absolute difference in risk of death was 2.3% [95% confidence interval (CI): 0.8-3.9] at 90 days and 4.7% (95% CI: 2.6-6.7) at 1 year. DSWI was independently associated with 90-day [adjusted relative risk (aRR) 1.89 (95% CI: 1.38-2.59)], 1-year [aRR 2.13 (95% CI: 1.68-2.71)] and long-term all-cause mortality [adjusted hazard ratio 1.56 (95% CI: 1.30-1.88)]. CONCLUSIONS: Both short- and long-term mortality risks are higher in DSWI patients compared to non-DSWI patients. These results stress the importance of preventing these infections and careful postoperative monitoring of DSWI patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Annan klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Other Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Deep sternal wound infection
- Mediastinitis
- Cardiac surgery
- Incidence
- Mortality
- Cardiac surgery
- Deep sternal wound infection
- Incidence
- Mediastinitis
- Mortality
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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