SwePub
Sök i LIBRIS databas

  Utökad sökning

id:"swepub:oai:DiVA.org:uu-470056"
 

Sökning: id:"swepub:oai:DiVA.org:uu-470056" > Retrospective, Mult...

Retrospective, Multicenter Analysis Comparing Conventional with Oncoplastic Breast Conserving Surgery : Oncological and Surgical Outcomes in Women with High-Risk Breast Cancer from the OPBC-01/iTOP2 Study

Fitzal, Florian (författare)
Med Univ Vienna, Dept Gen Surg, Vienna, Austria.;Med Univ Vienna, Breast Hlth Ctr, Vienna, Austria
Bolliger, Michael (författare)
Med Univ Vienna, Dept Gen Surg, Vienna, Austria.;Med Univ Vienna, Breast Hlth Ctr, Vienna, Austria
Dunkler, Daniela (författare)
Med Univ Vienna, Ctr Med Stat Informat & Intelligent Syst, Vienna, Austria
visa fler...
Geroldinger, Angelika (författare)
Med Univ Vienna, Ctr Med Stat Informat & Intelligent Syst, Vienna, Austria
Gambone, Luca (författare)
Med Univ Vienna, Dept Gen Surg, Vienna, Austria.;Med Univ Vienna, Breast Hlth Ctr, Vienna, Austria
Heil, Joerg (författare)
Heidelberg Univ Hosp, Breast Ctr, Dept Obstet & Gynecol, Heidelberg, Germany
Riedel, Fabian (författare)
Heidelberg Univ Hosp, Breast Ctr, Dept Obstet & Gynecol, Heidelberg, Germany
de Boniface, Jana (författare)
Karolinska Institutet
André, Camilla (författare)
Uppsala universitet,Endokrinkirurgi,Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden
Matrai, Zoltan (författare)
Natl Inst Oncol, Dept Breast & Sarcoma Surg, Budapest, Hungary
Pukancsik, David (författare)
Natl Inst Oncol, Dept Breast & Sarcoma Surg, Budapest, Hungary
Paulinelli, Regis R. (författare)
Univ Fed Goias, Araujo Jorge Hosp, Goias Anticanc Assoc, Goiania, Go, Brazil.
Ostapenko, Valerijus (författare)
Natl Canc Inst Vilnius Lithuania, Vilnius, Lithuania.;Univ Vilnius, Fac Med, Vilnius, Lithuania
Burneckis, Arvydas (författare)
Natl Canc Inst Vilnius Lithuania, Vilnius, Lithuania.;Univ Vilnius, Fac Med, Vilnius, Lithuania
Ostapenko, Andrej (författare)
Natl Canc Inst Vilnius Lithuania, Vilnius, Lithuania.;Univ Vilnius, Fac Med, Vilnius, Lithuania
Ostapenko, Edvin (författare)
Natl Canc Inst Vilnius Lithuania, Vilnius, Lithuania.;Univ Vilnius, Fac Med, Vilnius, Lithuania
Meani, Francesco (författare)
Ctr Senol Svizzera Italiana CSSI, Lugano, Switzerland.;Ente Osped Cantonale EOC, Dept Obstet & Gynecol, Lugano, Switzerland
Harder, Yves (författare)
Ctr Senol Svizzera Italiana CSSI, Lugano, Switzerland.;Ente Osped Cantonale EOC, Dept Plast Reconstruct & Aesthet Surg, Lugano, Switzerland.;Univ Svizzera Italiana USI, Fac Biomed Sci, Lugano, Switzerland
Bonollo, Marta (författare)
Ctr Senol Svizzera Italiana CSSI, Lugano, Switzerland.;Ente Osped Cantonale EOC, Dept Obstet & Gynecol, Lugano, Switzerland
Alberti, Andrea S. M. (författare)
Ctr Senol Svizzera Italiana CSSI, Lugano, Switzerland.;Ente Osped Cantonale EOC, Dept Plast Reconstruct & Aesthet Surg, Lugano, Switzerland.;Univ Svizzera Italiana USI, Fac Biomed Sci, Lugano, Switzerland
Tausch, Christoph (författare)
Breast Ctr, Zurich, Switzerland
Papassotiropoulos, Baerbel (författare)
Breast Ctr, Zurich, Switzerland
Helfgott, Ruth (författare)
Ordensklinikum Linz Sisters Charity, Dept Surg, Linz, Austria
Heck, Dietmar (författare)
Ordensklinikum Linz Sisters Charity, Dept Surg, Linz, Austria
Fehrer, Hans-Joerg (författare)
Ordensklinikum Linz Sisters Charity, Dept Surg, Linz, Austria
Acko, Markus (författare)
Ordensklinikum Linz Sisters Charity, Dept Surg, Linz, Austria
Schrenk, Peter (författare)
Med Univ Graz, Dept Obstet & Gynecol, Graz, Austria
Trapp, Elisabeth K. (författare)
Med Univ Graz, Dept Obstet & Gynecol, Graz, Austria
Gunda, Pristauz-Telsnigg (författare)
Med Univ Graz, Dept Obstet & Gynecol, Graz, Austria
Clara, Paliczek (författare)
Med Univ Graz, Dept Obstet & Gynecol, Graz, Austria
Montagna, Giacomo (författare)
Univ Hosp Basel, Breast Ctr, Basel, Switzerland.;Mem Sloan Kettering Canc Ctr, Dept Surg, Breast Serv, New York, NY 10021 USA
Ritter, Mathilde (författare)
Univ Hosp Basel, Breast Ctr, Basel, Switzerland
Blohmer, Jens-Uwe (författare)
Charite, Dept Gynecol, Campus Charite Mitte, Berlin, Germany.;Charite, Breast Ctr, Campus Charite Mitte, Berlin, Germany
Steffen, Sander (författare)
Univ Med Ctr Berlin, Charite Comprehens Canc Ctr CCCC, Clin Canc Registry, Berlin, Germany
Romics, Laszlo (författare)
NHS Greater Glasgow & Clyde, New Victoria Hosp, Glasgow, Lanark, Scotland
Morrow, Elizabeth (författare)
Univ Glasgow, Dept Acad Surg, Glasgow, Lanark, Scotland
Lorenz, Katharina (författare)
Cantonal Hosp Frauenfeld, Dept Gynecol & Obstet, Frauenfeld, Switzerland
Fehr, Mathias (författare)
Cantonal Hosp Frauenfeld, Dept Gynecol & Obstet, Frauenfeld, Switzerland
Weber, Walter Paul (författare)
Univ Hosp Basel, Breast Ctr, Basel, Switzerland.;Univ Basel, Basel, Switzerland
visa färre...
Med Univ Vienna, Dept Gen Surg, Vienna, Austria;Med Univ Vienna, Breast Hlth Ctr, Vienna, Austria Med Univ Vienna, Ctr Med Stat Informat & Intelligent Syst, Vienna, Austria (creator_code:org_t)
2021-10-13
2022
Engelska.
Ingår i: Annals of Surgical Oncology. - : Springer Nature. - 1068-9265 .- 1534-4681. ; 29:2, s. 1061-1070
Relaterad länk:
https://doi.org/10.1...
visa fler...
https://uu.diva-port... (primary) (Raw object)
https://link.springe...
https://urn.kb.se/re...
https://doi.org/10.1...
http://kipublication...
visa färre...
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Introduction Recent data suggest that margins >= 2 mm after breast-conserving surgery may improve local control in invasive breast cancer (BC). By allowing large resection volumes, oncoplastic breast-conserving surgery (OBCII; Clough level II/Tubingen 5-6) may achieve better local control than conventional breast conserving surgery (BCS; Tubingen 1-2) or oncoplastic breast conservation with low resection volumes (OBCI; Clough level I/Tubingen 3-4). Methods Data from consecutive high-risk BC patients treated in 15 centers from the Oncoplastic Breast Consortium (OPBC) network, between January 2010 and December 2013, were retrospectively reviewed. Results A total of 3,177 women were included, 30% of whom were treated with OBC (OBCI n = 663; OBCII n = 297). The BCS/OBCI group had significantly smaller tumors and smaller resection margins compared with OBCII (pT1: 50% vs. 37%, p = 0.002; proportion with margin <1 mm: 17% vs. 6%, p < 0.001). There were significantly more re-excisions due to R1 ("ink on tumor") in the BCS/OBCI compared with the OBCII group (11% vs. 7%, p = 0.049). Univariate and multivariable regression analysis adjusted for tumor biology, tumor size, radiotherapy, and systemic treatment demonstrated no differences in local, regional, or distant recurrence-free or overall survival between the two groups. Conclusions Large resection volumes in oncoplastic surgery increases the distance from cancer cells to the margin of the specimen and reduces reexcision rates significantly. With OBCII larger tumors are resected with similar local, regional and distant recurrence-free as well as overall survival rates as BCS/OBCI.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy