Sökning: id:"swepub:oai:DiVA.org:uu-476435" >
Reflections on the ...
Reflections on the usefulness of today’s atrial fibrillation ablation procedure endpoints and patient-reported outcomes
-
- Blomström-Lundqvist, Carina (författare)
- Uppsala universitet,Kardiologi-arrytmi
-
- Svedung Wettervik, Victoria, 1994- (författare)
- Uppsala universitet,Kardiologi-arrytmi
-
(creator_code:org_t)
- 2022-06-06
- 2022
- Engelska.
-
Ingår i: Europace. - : Oxford University Press (OUP). - 1099-5129 .- 1532-2092. ; 24:Supplement_2, s. ii29-ii43
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- The improvement of Patient-reported outcomes, such as health-related quality of life, is the main indication for atrial fibrillation ablation. Despite this guideline derived indication for an AF ablation procedure the current standardized primary endpoint in AF ablation trials is still rhythm-related, and primarily a 30-second long AF episode. The review presents reflections on the non-rational arguments of using rhythm related endpoints rather than Patient-reported outcomes in AF ablation procedure trials despite the mismatch between many of the rhythm related variables and symptoms. Arguments for health-related quality of life as the most optimal primary endpoint in clinical trials are presented while atrial fibrillation burden is presented as the most optimal electrical complementary endpoint, apart from being the major variable in mechanistic trials.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Cardiology
- Kardiologi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
-
Europace
(Sök värdpublikationen i LIBRIS)
Till lärosätets databas