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Aberrant callosal m...
Aberrant callosal morphology in ex-smokers
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- Dale, Caitlin (författare)
- Univ Auckland, Sch Psychol, Auckland 1010, New Zealand
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- Kalantary, Delshad (författare)
- Univ Auckland, Fac Med & Hlth Sci, Ctr Brain Res, Dept Anat & Med Imaging, Auckland 1023, New Zealand
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- Luders, Eileen (författare)
- Uppsala universitet,Reproduktiv hälsa,Univ Auckland, Sch Psychol, Auckland 1010, New Zealand; Univ Southern Calif, Sch Med, Lab Neuro Imaging, Los Angeles, CA 90033 USA
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- Kurth, Florian (författare)
- Univ Auckland, Sch Psychol, Auckland 1010, New Zealand
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(creator_code:org_t)
- IMR Press, 2022
- 2022
- Engelska.
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Ingår i: Journal of Integrative Neuroscience. - : IMR Press. - 0219-6352 .- 1757-448X. ; 21:4
- Relaterad länk:
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
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- Background: Cigarette smoking is associated with widespread structural alterations in both brain hemispheres as well as of the corpus callosum (i.e., the brain???s main interhemispheric white matter pathway). While similar hemispheric alterations have also been reported in ex-smokers, no study has yet examined the corpus callosum in ex-smokers.Methods: We compared callosal morphology in a sample of 107 ex-smokers (57 males/50 females) and 193 non-smokers (73 males/120 females), aged between 42 and 97 years. More specifically, we measured the total callosal area as well as seven callosal subregions using the Witelson parcellation scheme.Results: At uncorrected levels, we detected significantly smaller callosal areas in ex-smokers than in non-smokers within the posterior midbody, genu, and isthmus (albeit the latter only on a trend level). When applying corrections for multiple comparisons, only the effect within the posterior midbody remained significant.Conclusions: Our findings suggest a weaker interhemispheric connectivity in ex-smokers compared to non-smokers, specifically between frontal and temporal areas.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- brain
- corpus callosum
- ex-smokers
- posterior midbody
- smoking
- structural MRI
- white matter
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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