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Effects of One Nigh...
Effects of One Night of Forced Wakefulness on Morning Resting Blood Pressure in Humans : The Role of Biological Sex and Weight Status
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- van Egmond, Lieve (författare)
- Uppsala universitet,Funktionell farmakologi och neurovetenskap,Institutionen för farmaceutisk biovetenskap
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- Xue, Pei (författare)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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- Meth, Elisa (författare)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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- Ilemosoglou, Maria (författare)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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- Engström, Joachim (författare)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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- Benedict, Christian, Docent, 1976- (författare)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap
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(creator_code:org_t)
- 2022-09-14
- 2022
- Engelska.
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Ingår i: Clocks & Sleep. - : MDPI. - 2624-5175. ; 4:3, s. 458-465
- Relaterad länk:
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- Permanent night shift work is associated with adverse health effects, including elevated blood pressure (BP) and hypertension. Here, we examined the BP response to one night of forced wakefulness in a sitting position in a cohort without night shift work experience. According to a counterbalanced crossover design, 47 young adults with either obesity (N = 22; 10 women) or normal weight (N = 25; 11 women) participated in one night of sleep and one night of forced wakefulness under in-laboratory conditions. Resting ankle and brachial arterial BP were assessed in the morning, i.e., the time of the day when adverse cardiovascular events peak. After forced wakefulness, diastolic and mean arterial BP were similar to 4 mmHg higher at the ankle site and similar to 3 mmHg higher at the brachial site than after regular sleep (p < 0.05). The increase in BP following overnight forced wakefulness was more pronounced among men vs. women and more significant for diastolic BP at both sites among participants with normal weight vs. those with obesity. If confirmed in larger cohorts, including 24 h BP monitoring, people with occupations involving night shifts might benefit from regular BP monitoring. Particular attention should be paid to possible sex- and weight-specific effects of night shift work on BP.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- sleep deprivation
- blood pressure
- sex differences
- obesity
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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