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Reference equations...
Reference equations for breathlessness during incremental cycle exercise testing
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- Elmberg, Viktor (author)
- Lund University,Lunds universitet,Lungmedicin, allergologi och palliativ medicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Andfåddhet och kronisk andningssvikt,Forskargrupper vid Lunds universitet,Respiratory Medicine, Allergology, and Palliative Medicine,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Breathlessness and chronic respiratory failure,Lund University Research Groups,Blekinge Hospital,Lund Univ, Sweden; Blekinge Hosp, Sweden
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- Schiöler, Linus, 1977 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
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- Lindow, Thomas (author)
- Kolling Institute of Medical Research,Växjö Central Hospital,Vaxjo Cent Hosp, Sweden; Univ Sydney, Australia
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- Hedman, Kristofer (author)
- Linköpings universitet,Linköping University,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Fysiologiska kliniken US
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- Malinovschi, Andrei, 1978- (author)
- Uppsala University,Uppsala universitet,Klinisk fysiologi,Uppsala Univ, Sweden
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- Lewthwaite, Hayley (author)
- University of South Australia,Univ Newcastle, Australia; Univ South Australia, Australia
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- Jensen, Dennis (author)
- McGill University Health Center,McGill University,McGill Univ, Canada; McGill Univ, Canada
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- Brudin, Lars (author)
- Kalmar County Hospital,Kalmar Cty Hosp, Sweden
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- Ekström, Magnus (author)
- Lund University,Lunds universitet,Lungmedicin, allergologi och palliativ medicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Palliativt Utvecklingscentrum,Forskargrupper vid Lunds universitet,Andfåddhet och kronisk andningssvikt,Respiratory Medicine, Allergology, and Palliative Medicine,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,The Institute for Palliative Care,Lund University Research Groups,Breathlessness and chronic respiratory failure,Lund Univ, Sweden
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(creator_code:org_t)
- 2023-03-16
- 2023
- English.
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In: ERJ Open Research. - : European Respiratory Society. - 2312-0541. ; 9:2
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Abstract
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- BACKGROUND: Exertional breathlessness is commonly assessed using incremental exercise testing (IET), but reference equations for breathlessness responses are lacking. We aimed to develop reference equations for breathlessness intensity during IET.METHODS: A retrospective, consecutive cohort study of adults undergoing IET was carried out in Sweden. Exclusion criteria included cardiac or respiratory disease, death or any of the aforementioned diagnoses within 1 year of the IET, morbid obesity, abnormally low exercise capacity, submaximal exertion or an abnormal exercise test. Probabilities for breathlessness intensity ratings (Borg CR10) during IET in relation to power output (%predWmax), age, sex, height and body mass were analysed using marginal ordinal logistic regression. Reference equations for males and females were derived to predict the upper limit of normal (ULN) and the probability of different Borg CR10 intensity ratings.RESULTS: 2581 participants (43% female) aged 18-90 years were included. Mean breathlessness intensity was similar between sexes at peak exertion (6.7±1.5 versus 6.4±1.5 Borg CR10 units) and throughout exercise in relation to %predWmax. Final reference equations included age, height and %predWmax for males, whereas height was not included for females. The models showed a close fit to observed breathlessness intensity ratings across %predWmax values. Models using absolute W did not show superior fit. Scripts are provided for calculating the probability for different breathlessness intensity ratings and the ULN by %predWmax throughout IET.CONCLUSION: We present the first reference equations for interpreting breathlessness intensity during incremental cycle exercise testing in males and females aged 18-90 years.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Physiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Idrottsvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Sport and Fitness Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- Lung Medicine
- Lungmedicin
- Physiology
- Fysiologi
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Elmberg, Viktor
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Schiöler, Linus, ...
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Lindow, Thomas
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Hedman, Kristofe ...
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Malinovschi, And ...
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Lewthwaite, Hayl ...
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show more...
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Jensen, Dennis
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Brudin, Lars
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Ekström, Magnus
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Respiratory Medi ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Physiology
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Sport and Fitnes ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
- Articles in the publication
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ERJ Open Researc ...
- By the university
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Uppsala University
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Lund University
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Linköping University
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University of Gothenburg