Sökning: id:"swepub:oai:DiVA.org:uu-519964" >
Putative volatile b...
Putative volatile biomarkers of bovine tuberculosis infection in breath, skin and feces of cattle
-
- Brebu, Mihai (författare)
- Petru Poni Inst Macromol Chem, Aleea Grigore Gh Voda 41A, Iasi 700487, Romania.
-
- Simion, Violeta Elena (författare)
- Spiru Haret Univ, Fac Vet Med, Bd Basarabia 256, Bucharest 030171, Romania.
-
- Andronie, Viorel (författare)
- Spiru Haret Univ, Fac Vet Med, Bd Basarabia 256, Bucharest 030171, Romania.
-
visa fler...
-
- Jaimes-Mogollon, Aylen Lisset (författare)
- Univ Pamplona, Fac Engn & Architecture, GISM Grp, Via Bucaramanga Km 1, Pamplona 543050, Colombia.
-
- Beleno-Saenz, Kelvin de Jesus (författare)
- Univ Pamplona, Fac Engn & Architecture, GISM Grp, Via Bucaramanga Km 1, Pamplona 543050, Colombia.;Univ Autonoma Caribe, Dept Mechatron Engn, Calle 90 46-112, Barranquilla 080020, Colombia.
-
- Ionescu, Florina (författare)
- Uppsala universitet,Institutionen för materialvetenskap
-
- Welearegay, Tesfalem (författare)
- Uppsala universitet,Fasta tillståndets fysik
-
- Suschinel, Raluca (författare)
- Estonian Univ Life Sci, Inst Vet Med & Anim Sci, Kreutzwaldi 62, EE-51006 Tartu, Estonia.
-
- de Lema, Jose Bruno (författare)
- Estonian Univ Life Sci, Inst Vet Med & Anim Sci, Kreutzwaldi 62, EE-51006 Tartu, Estonia.;D Asociat, Paseo Montana 14, Granollers 08402, Barcelona, Spain.
-
- Ionescu, Radu (författare)
- D Asociat, Paseo Montana 14, Granollers 08402, Barcelona, Spain.
-
visa färre...
-
Petru Poni Inst Macromol Chem, Aleea Grigore Gh Voda 41A, Iasi 700487, Romania Spiru Haret Univ, Fac Vet Med, Bd Basarabia 256, Bucharest 030171, Romania. (creator_code:org_t)
- 2023-02-25
- 2023
- Engelska.
-
Ingår i: Molecular and Cellular Biochemistry. - : Springer. - 0300-8177 .- 1573-4919. ; 478:11, s. 2473-2480
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Bovine tuberculosis (bTB) is an infectious disease with significant impact on animal health, public health and international trade. Standard bTB screening in live cattle consists in injecting tuberculin and measuring the swelling at the place of injection few days later. This procedure is expensive, time-consuming, logistically challenging, and is not conclusive before performing confirmatory tests and additional analysis. The analysis of the volatile organic compounds (VOCs) emitted by non-invasive biological samples can provide an alternative diagnostic approach suitable for bTB screening. In the present study, we analyzed VOC samples emitted through the breath, feces and skin of 18 cows diagnosed with bTB from three farms from Romania, as well as of 27 negative cows for bTB from the same farms. Analytical studies employing gas chromatography coupled to mass spectrometry revealed 80 VOCs emitted through the breath, 200 VOCs released by feces, and 80 VOCs emitted through the skin. Statistical analysis of these compounds allowed the identification of 3 tentative breath VOC biomarkers (acetone; 4-methyldecane; D-limonene), 9 tentative feces VOC biomarkers (toluene; [(1,1-dimethylethyl)thio]acetic acid; alpha-thujene; camphene; phenol; o-cymene; 3-(1,1-dimethylethyl)-2,2,4,4-tetramethyl-3-pentanol; 2,5-dimethylhexane-2,5-dihydroperoxide; 2,4-di-tert-butylphenol), and 3 tentative skin VOC biomarkers (ammonia; 1-methoxy-2-propanol; toluene). The possible pathway of these volatile biomarkers is discussed.
Ämnesord
- NATURVETENSKAP -- Biologi -- Mikrobiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Microbiology (hsv//eng)
Nyckelord
- Bovine tuberculosis
- Breath
- Feces
- Skin
- GC-MS
- Volatile biomarkers
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Brebu, Mihai
-
Simion, Violeta ...
-
Andronie, Viorel
-
Jaimes-Mogollon, ...
-
Beleno-Saenz, Ke ...
-
Ionescu, Florina
-
visa fler...
-
Welearegay, Tesf ...
-
Suschinel, Raluc ...
-
de Lema, Jose Br ...
-
Ionescu, Radu
-
visa färre...
- Om ämnet
-
- NATURVETENSKAP
-
NATURVETENSKAP
-
och Biologi
-
och Mikrobiologi
- Artiklar i publikationen
-
Molecular and Ce ...
- Av lärosätet
-
Uppsala universitet