National long-term patient-reported outcomes following mastectomy with or without breast reconstruction: The Swedish Breast Reconstruction Outcome Study Part 2 (SweBRO 2)

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National long-term patient-reported outcomes following mastectomy with or without breast reconstruction : The Swedish Breast Reconstruction Outcome Study Part 2 (SweBRO 2)

Gümüscü, Rojda (författare): Uppsala University,Uppsala universitet,Plastikkirurgi,Uppsala Univ Hosp, Dept Plast & Reconstruct Surg, SE-75185 Uppsala, Sweden.,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

Unukovych, Dmytro (författare): Uppsala University,Uppsala universitet,Institutionen för kirurgiska vetenskaper,Karolinska Univ Hosp, Dept Plast & Craniofacial Surg, Stockholm, Sweden.,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Department of Plastic and Craniofacial Surgery, Karolinska University Hospital, Stockholm, Sweden

Wärnberg, Fredrik (författare): Uppsala University,Gothenburg University,Göteborgs universitet,Uppsala universitet,Institutionen för kirurgiska vetenskaper,Gothenburg Univ, Sahlgrenska Univ Hosp, Inst Clin Sci, Dept Surg,Sahlgrenska Acad, Gothenburg, Sweden.,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Department of Surgery, Sahlgrenska University Hospital, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden

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de Boniface, Jana (författare): Karolinska Institute,Capio St. Görans Sjukhus,Capio St Gorans Hosp, Dept Surg, Stockholm, Sweden.;Karolinska Intitutet, Dept Med & Surg, Stockholm, Sweden.

Sund, Malin (författare): Umeå University,Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Department of Surgery, University of Helsinki, Helsinki University Hospital, Helsinki, Finland,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.;Univ Helsinki, Dept Surg, Helsinki, Finland.;Helsinki Univ Hosp, Helsinki, Finland.

Åhsberg, Kristina (författare): Lund University,Lunds universitet,Bröstcancerkirurgi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Breast Cancer Surgery,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Halmstad County Hospital,Halland Hosp, Dept Surg, Halmstad, Sweden.;Lund Univ, Dept Clin Sci, Lund, Sweden.

Hansson, Emma, 1981 (författare): Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för plastikkirurgi,Institute of Clinical Sciences, Department of Plastic Surgery,Department of Plastic Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Plastic and Reconstructive Surgery, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden,Univ Gothenburg, Inst Clin Sci, Sahlgrenska Acad, Dept Plast Surg, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Dept Plast & Reconstruct Surg, Reg Vastra Gotaland, Gothenburg, Sweden.

Folkvaljon, Folke (författare): Sveastat AB, Gothenburg, Sweden.,Sveastat AB, Göteborg, Sweden

Mani, Maria (författare): Uppsala University,Uppsala universitet,Plastikkirurgi,Uppsala Univ Hosp, Dept Plast & Reconstruct Surg, SE-75185 Uppsala, Sweden.,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Department of Plastic and Reconstructive Surgery, Uppsala University Hospital, Uppsala, Sweden

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Oxford University Press, 2024
2024
Engelska.
Ingår i: BJS Open. - : Oxford University Press. - 2474-9842. ; 8:1

Relaterad länk:: https://doi.org/10.1...; visa fler...; https://uu.diva-port... (primary) (Raw object); https://umu.diva-por... (primary) (Raw object); http://dx.doi.org/10... (free); https://urn.kb.se/re...; https://doi.org/10.1...; https://gup.ub.gu.se...; https://urn.kb.se/re...; https://lup.lub.lu.s...; http://kipublication...; visa färre...

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Background: The Swedish Breast Reconstruction Outcome Study (SweBRO) initiative is a nationwide study with the primary aim of assessing long-term outcomes after mastectomy with and without breast reconstruction (BR). The current part (SweBRO 2) is designed to evaluate health-related quality of life (HRQoL), with the hypothesis that BR has a positive impact on patient-reported HRQoL in the long-term.Methods: Women who underwent mastectomy in Sweden in 2000, 2005, or 2010 and were alive at the time of the survey were identified through the National Breast Cancer Registry. Eligible participants received formal invitation letters to take part in a survey evaluating their HRQoL at 5 , 10, or 15 years post-mastectomy. The EORTC QLQ-C30, EORTC QLQ-BR23, and EQ-5D-3L questionnaires were employed.Results: Of 2904 respondents (50% of 5853 invited), 895 (31%) had received BR. Among them, 516 (58%) were reconstructed with implants and 281 (31%) with autologous tissue. Women with BR scored significantly better in the EORCT QLQ-C30 physical functioning domain (mean 90 versus 81 points), fatigue (mean 21 versus 25), and dyspnoea (mean 16 versus 22) compared to non-reconstructed women. The EORTC QLQ-BR23 revealed that women with BR experienced favourable sexual functioning compared with non-reconstructed women (mean 26 versus 14). The EQ-5D-3L visual analogue scale score was similar between groups.Conclusion: The current study underscores the benefits of BR for long-term well-being, for example, in terms of physical and sexual functioning. These underline the importance of informing women undergoing mastectomy about BR alternatives and its potential benefits in enhancing long-term well-being. The Swedish Breast Reconstruction Outcome Study (SweBRO) initiative is a nationwide study with the primary aim of assessing long-term outcomes after mastectomy with and without breast reconstruction (BR). Women who had undergone mastectomy in Sweden in 2000, 2005, or 2010 and were alive at the time of the survey were identified through the National Breast Cancer Registry. The current study underscores the benefits of BR for long-term well-being, for example, in terms of physical and sexual functioning.

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Av författaren/redakt...: Gümüscü, Rojda; Unukovych, Dmytr ...; Wärnberg, Fredri ...; de Boniface, Jan ...; Sund, Malin; Åhsberg, Kristin ...; visa fler...; Hansson, Emma, 1 ...; Folkvaljon, Folk ...; Mani, Maria; visa färre...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kirurgi

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Av lärosätet: Uppsala universitet; Göteborgs universitet; Umeå universitet; Lunds universitet; Karolinska Institutet

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National long-term patient-reported outcomes following mastectomy with or without breast reconstruction : The Swedish Breast Reconstruction Outcome Study Part 2 (SweBRO 2)

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